Pyroptosis, apoptosis and necroptosis are the most genetically well-defined programmed
cell death (PCD) pathways, and they are intricately involved in both homeostasis and …

Programmed cell death plays crucial roles in organismal development and host defense.
Recent studies have highlighted mechanistic overlaps and extensive, multifaceted crosstalk …

Pyroptosis, apoptosis, and necroptosis are mainly programmed cell death (PCD) pathways
for host defense and homeostasis. PANoptosis is a newly distinct inflammatory PCD …

Programmed cell death is regulated by evolutionarily conserved pathways that play critical
roles in development and the immune response. A newly recognized pathway for …

The innate immune system provides the first line of defense against cellular perturbations.
Innate immune activation elicits inflammatory programmed cell death in response to …

PANoptosis, a new research hotspot at the moment, is a cell death pattern in which
pyroptosis, apoptosis, and necroptosis all occur in the same cell population. In essence …

Programmed cell death (PCD) is a key mechanism for the study of anticancer drugs and has
a significant impact on the development and management of cancer. A growing amount of …

PANoptosis is a new cell death proposed by Malireddi et al in 2019, which is characterized
by pyroptosis, apoptosis and necroptosis, but cannot be explained by any of them alone …

In the past decade, emerging viral outbreaks like SARS-CoV-2, Zika and Ebola have
presented major challenges to the global health system. Viruses are unique pathogens in …

In response to infection or sterile insults, inflammatory programmed cell death is an essential
component of the innate immune response to remove infected or damaged cells …