[HTML][HTML] Qiliqiangxin attenuates phenylephrine-induced cardiac hypertrophy through downregulation of MiR-199a-5p

H Zhang, S Li, Q Zhou, Q Sun, S Shen, Y Zhou… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Qiliqiangxin (QL), a traditional Chinese medicine, has long been used to
treat chronic heart failure. Previous studies demonstrated that QL could prevent cardiac …

Qiliqiangxin inhibits the development of cardiac hypertrophy, remodeling, and dysfunction during 4 weeks of pressure overload in mice

Y Zou, L Lin, Y Ye, J Wei, N Zhou, Y Liang… - Journal of …, 2012 - journals.lww.com
Qiliqiangxin (QL), a traditional Chinese medicine, has been used in the treatment of chronic
heart failure. However, whether QL can benefit cardiac remodeling in the hypertensive state …

Qiliqiangxin inhibits angiotensin II‐induced transdifferentiation of rat cardiac fibroblasts through suppressing interleukin‐6

J Zhou, K Jiang, X Ding, M Fu, S Wang… - Journal of cellular …, 2015 - Wiley Online Library
Qiliqiangxin (QL), a traditional Chinese medicine, had long been used to treat chronic heart
failure. Recent studies revealed that differentiation of cardiac fibroblasts (CFs) into …

[HTML][HTML] Qiliqiangxin attenuates cardiac remodeling via inhibition of TGF-β1/Smad3 and NF-κB signaling pathways in a rat model of myocardial infarction

A Han, Y Lu, Q Zheng, J Zhang, YZ Zhao… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Qiliqiangxin (QL), a traditional Chinese medicine, has been
demonstrated to be effective and safe for the treatment of chronic heart failure. Left …

Qiliqiangxin improves cardiac function and attenuates cardiac remodelling in doxorubicin-induced heart failure rats

X Sun, G Chen, Y Xie, D Jiang, J Han… - Pharmaceutical …, 2020 - Taylor & Francis
Context Therapeutic doxorubicin administration is restricted as this anticancer drug may be
cardiotoxic. The traditional Chinese medicine qiliqiangxin has been approved for clinical …

[HTML][HTML] Future prospects of Qiliqiangxin on heart failure: epigenetic regulation of regeneration

L Tao, S Shen, X Li - Frontiers in Genetics, 2013 - frontiersin.org
Qiliqiangxin (QL), a traditional Chinese medicine, was approved by China Food and Drug
Administration for the treatment of heart failure in 2004 (Li et al., 2013). Our recent …

[HTML][HTML] Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic pressure Overload–induced Cardiac Hypertrophy and …

Y Ye, H Gong, X Wang, J Wu, S Wang… - Journal of …, 2015 - journals.lww.com
We previously showed that Qiliqiangxin (QL) capsules could ameliorate cardiac hypertrophy
and remodeling in a mouse model of pressure overload. Here, we compared the effects of …

[HTML][HTML] Traditional Chinese medicine Qiliqiangxin attenuates phenylephrine-induced cardiac hypertrophy via upregulating PPARγ and PGC-1α

RR Gao, XD Wu, HM Jiang, YJ Zhu… - Annals of …, 2018 - ncbi.nlm.nih.gov
Background Clinical study has demonstrated that the traditional Chinese medicine
Qiliqiangxin (QLQX) has protective effects on heart failure. Phenylephrine (PE) is an …

[HTML][HTML] Traditional Chinese medication Qiliqiangxin protects against cardiac remodeling and dysfunction in spontaneously hypertensive rats

H Wang, X Zhang, P Yu, Q Zhou, J Zhang… - … Journal of Medical …, 2017 - ncbi.nlm.nih.gov
Qiliqiangxin (QLQX), a traditional Chinese herbs medication, exerted protective effect in
chronic heart failure patients in a multicenter randomized double-blind study. QLQX has also …

[HTML][HTML] Traditional Chinese Medication Qiliqiangxin attenuates cardiac remodeling after acute myocardial infarction in mice

L Tao, S Shen, S Fu, H Fang, X Wang, S Das… - Scientific Reports, 2015 - nature.com
In a multicenter randomized double-blind study we demonstrated that Qiliqiangxin (QLQX), a
traditional Chinese medicine, had a protective effect in heart failure patients. However …