MeCP2 is critical within HoxB1-derived tissues of mice for normal lifespan
Rett syndrome is a neurodevelopmental disorder caused by mutations in methyl-CpG-
binding protein 2 (MECP2), a transcriptional regulator. In addition to cognitive …
binding protein 2 (MECP2), a transcriptional regulator. In addition to cognitive …
Loss of MeCP2 function across several neuronal populations impairs breathing response to acute hypoxia
Rett Syndrome (RTT) is a neurodevelopmental disorder caused by loss of function of the
transcriptional regulator Methyl-CpG-Binding Protein 2 (MeCP2). In addition to the …
transcriptional regulator Methyl-CpG-Binding Protein 2 (MeCP2). In addition to the …
Progressive changes in a distributed neural circuit underlie breathing abnormalities in mice lacking MeCP2
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in Methyl-CpG-
binding protein 2 (MECP2). Severe breathing abnormalities are common in RTT and are …
binding protein 2 (MECP2). Severe breathing abnormalities are common in RTT and are …
Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice
JC Viemari, JC Roux, AK Tryba, V Saywell… - Journal of …, 2005 - Soc Neuroscience
Rett syndrome is a severe X-linked neurological disorder in which most patients have
mutations in the methyl-CpG binding protein 2 (MECP2) gene and suffer from bioaminergic …
mutations in the methyl-CpG binding protein 2 (MECP2) gene and suffer from bioaminergic …
Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice
JM Bissonnette, SJ Knopp - Pediatric research, 2006 - nature.com
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the X-linked
gene methyl-CpG-binding protein 2 (MECP2) that encodes a DNA binding protein involved …
gene methyl-CpG-binding protein 2 (MECP2) that encodes a DNA binding protein involved …
Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome
L Robinson, J Guy, L McKay, E Brockett, RC Spike… - Brain, 2012 - academic.oup.com
Rett syndrome is a neurological disorder caused by mutation of the X-linked MECP2 gene.
Mice lacking functional Mecp2 display a spectrum of Rett syndrome-like signs, including …
Mice lacking functional Mecp2 display a spectrum of Rett syndrome-like signs, including …
Rescue of behavioral and EEG deficits in male and female Mecp2-deficient mice by delayed Mecp2 gene reactivation
Mutations of the X-linked gene encoding methyl CpG binding protein type 2 (MECP2) are
the predominant cause of Rett syndrome, a severe neurodevelopmental condition that …
the predominant cause of Rett syndrome, a severe neurodevelopmental condition that …
Cell-specific expression of wild-type MeCP2 in mouse models of Rett syndrome yields insight about pathogenesis
M Alvarez-Saavedra, MA Sáez, D Kang… - Human molecular …, 2007 - academic.oup.com
Rett syndrome (RTT), a leading cause of mental retardation with autistic features in females,
is caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MeCP2). RTT is …
is caused by mutations in the gene encoding methyl-CpG-binding protein 2 (MeCP2). RTT is …
Respiratory phenotypes are distinctly affected in mice with common Rett syndrome mutations MeCP2 T158A and R168X
JM Bissonnette, LR Schaevitz, SJ Knopp, Z Zhou - Neuroscience, 2014 - Elsevier
Respiratory disturbances are a primary phenotype of the neurological disorder, Rett
syndrome (RTT), caused by mutations in the X-linked gene encoding methyl-CpG-binding …
syndrome (RTT), caused by mutations in the X-linked gene encoding methyl-CpG-binding …
Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome
The postnatal neurodevelopmental disorder Rett syndrome, caused by mutations in MECP2,
produces a diverse array of symptoms, including loss of language, motor, and social skills …
produces a diverse array of symptoms, including loss of language, motor, and social skills …