Cost‐effectiveness of adrenocorticotropic hormone versus oral steroids for infantile spasms

I Sanchez Fernandez, M Amengual‐Gual… - …, 2021 - Wiley Online Library
Objective To compare the effectiveness and cost‐effectiveness of adrenocorticotropic
hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we …

Effectiveness of corticosteroids versus adrenocorticotropic hormone for infantile spasms: a systematic review and meta‐analysis

YH Chang, C Chen, SH Chen… - Annals of Clinical and …, 2019 - Wiley Online Library
Objective To compare the therapeutic effectiveness of oral corticosteroids with that of
adrenocorticotrophic hormone for infantile spasms. Methods PubMed, Embase, Scopus, and …

Hormonal therapy for infantile spasms: a systematic review and meta-analysis

S Guang, L Mao, L Zhong, F Liu, Z Pan, F Yin… - Frontiers in …, 2022 - frontiersin.org
Objective The limitations of adrenocorticotrophic hormone (ACTH) treatment for infantile
spasms (ISs), such as high costs, limited availability, and adverse effects (AEs), make it …

Effect of price increase of adrenocorticotropic hormone on treatment practices of infantile spasms

CD Wray, TA Benke - Pediatric neurology, 2010 - Elsevier
Intramuscular adrenocorticotropic hormone putatively constitutes the most efficacious
treatment for infantile spasms. Adrenocorticotropic hormone in the United States is an …

Prednisolone/prednisone as adrenocorticotropic hormone alternative for infantile spasms: a meta‐analysis of randomized controlled trials

S Li, X Zhong, S Hong, T Li… - Developmental Medicine & …, 2020 - Wiley Online Library
Aim To compare the efficacy and safety of prednisolone/prednisone and adrenocorticotropic
hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized …

Efficacy and safety of corticosteroids and ACTH in epileptic syndromes beyond Infantile Epileptic Spasms Syndrome (IESS): A systematic review and meta‐analysis

R Korinthenberg, T Bast, E Haberlandt, U Stephani… - …, 2024 - Wiley Online Library
We conducted a systematic review investigating the efficacy and tolerability of
adrenocorticotropic hormone (ACTH) and corticosteroids in children with epilepsies other …

High dose (4 mg/kg/day) versus usual dose (2 mg/kg/day) oral prednisolone for treatment of infantile spasms: an open-label, randomized controlled trial

P Chellamuthu, S Sharma, P Jain, JS Kaushik, A Seth… - Epilepsy research, 2014 - Elsevier
Objectives This study aimed to test the hypothesis that high-dose prednisolone (4
mg/kg/day) may be more efficacious than usual-dose (2 mg/kg/day) prednisolone for spasm …

Corticosteroids for the treatment of infantile spasms: a systematic review

R Arya, S Shinnar, TA Glauser - Journal of child neurology, 2012 - journals.sagepub.com
Adrenocorticotropic hormone (ACTH) and corticosteroids are the usual first-line treatment
options for infantile spasms. Despite significant differences, these agents are often lumped …

[HTML][HTML] Comparison of adrenocorticotropic hormone efficacy between aetiologies of infantile spasms

A Daida, S Hamano, K Hayashi, H Nonoyama… - Seizure, 2021 - Elsevier
Purpose We aimed to study the efficacy of adrenocorticotropic hormone (ACTH) treatment
on infantile spasms with different aetiologies. In particular, we were interested in patients …

Temporal trends in the cost and use of first‐line treatments for infantile epileptic spasms syndrome

I Sánchez Fernández, M Amengual‐Gual… - …, 2023 - Wiley Online Library
Objective To describe the temporal trends in the cost and use of adrenocorticotropic
hormone (ACTH), oral prednisolone, and vigabatrin, the first‐line treatments for infantile …