Adipose tissue biology and HIV-infection

M Giralt, P Domingo, F Villarroya - Best Practice & Research Clinical …, 2011 - Elsevier
HIV-1/highly active antiretroviral therapy-associated lipodystrophy syndrome (HALS) is an
adipose tissue redistribution disorder characterized by subcutaneous adipose tissue …

Lipodystrophy in HIV 1-infected patients: lessons for obesity research

F Villarroya, P Domingo, M Giralt - International journal of obesity, 2007 - nature.com
Lipodystrophy is a common alteration in HIV 1-infected patients under anti-retroviral
treatment. This syndrome is usually associated with peripheral lipoatrophy, central adiposity …

Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations

ML Gougeon, L Pénicaud, B Fromenty… - Antiviral …, 2004 - journals.sagepub.com
The recent clinical use of potent HIV-1 drugs, including nucleoside reverse transcriptase
inhibitors (NRTIs) and non-peptidic viral protease inhibitors (PIs), and their combinations …

HIV-1 infection alters gene expression in adipose tissue, which contributes to HIV-1/HAART-associated lipodystrophy

M Giralt, P Domingo, JP Guallar… - Antiviral …, 2006 - journals.sagepub.com
Background The aetiopathogenic bases of HIV-1-/highly active antiretroviral treatment
(HAART)-associated lipodystrophy (HALS) are poorly known, but this syndrome indicates …

Toxic metabolic syndrome associated with HAART

SB Haugaard - Expert opinion on drug metabolism & toxicology, 2006 - Taylor & Francis
Acquired fat redistribution, that is, peripheral fat loss often accompanied by central fat
accumulation in patients with HIV infection is the most common form of lipodystrophy in man …

[HTML][HTML] HIV-associated adipose redistribution syndrome (HARS): etiology and pathophysiological mechanisms

K Lichtenstein, A Balasubramanyam, R Sekhar… - AIDS research and …, 2007 - Springer
Human immunodeficiency virus (HIV)-associated adipose redistribution syndrome (HARS) is
a fat accumulation disorder characterized by increases in visceral adipose tissue. Patients …

Adipokines in the HIV/HAART-associated lipodystrophy syndrome

J Paruthi, N Gill, CS Mantzoros - Metabolism, 2013 - Elsevier
The use of highly active antiretroviral therapy (HAART) in the treatment of human
immunodeficiency virus has dramatically altered both the landscape of this disease and the …

Nutrition and the HIV-associated lipodystrophy syndrome

CR Loonam, A Mullen - Nutrition research reviews, 2012 - cambridge.org
HIV-associated lipodystrophy syndrome (HALS), comprising metabolic and morphological
alterations, is a known side effect of highly active antiretroviral therapy (HAART). Evidence …

Clinical perspectives on HIV-associated lipodystrophy syndrome: an update

A Shevitz, CA Wanke, J Falutz, DP Kotler - Aids, 2001 - journals.lww.com
In developed countries, the availability of highly active antiretroviral therapy (HAART) has
contributed to a dramatic decrease in mortality and opportunistic infections associated with …

The role of adipokines in relation to HIV lipodystrophy

LL Sweeney, AM Brennan, CS Mantzoros - Aids, 2007 - journals.lww.com
Background Changes in body fat distribution are a frequent finding in individuals with HIV
infection. Lipoatrophy, or decreased subcutaneous fat in the limbs together with prominent …