Hydrogen peroxide is a major redox signaling molecule underlying a novel paradigm of cell
function and communication. A role for H 2 O 2 as an intercellular signaling molecule and …

Background Controlled generation and removal of hydrogen peroxide play important roles
in cellular redox homeostasis and signaling. We used a hydrogen peroxide biosensor …

Reactive oxygen species (ROS) like hydrogen peroxide (H2O2) are transient species that
have broad actions in signaling and stress, but spatioanatomical understanding of their …

Abstract Hydrogen peroxide (H 2 O 2) has been identified recently as a meaningful signaling
molecule. The ability to perform imaging of H 2 O 2 in complex biological organisms with a …

Oxygen is essential to maintaining normal brain function. A large body of evidence suggests
that the partial pressure of oxygen (p O 2) in brain tissue is physiologically maintained within …

Understanding of redox signaling requires data on the spatiotemporal distribution of
hydrogen peroxide (H2O2) within the cell. The fluorescent reporter HyPer is a powerful …

As a signaling molecule in mammalian cells, hydrogen peroxide (H 2 O 2) determines the
thiol/disulfide oxidation state of several key proteins in the cytosol. Localization is a key …

Cellular metabolism provides various sources of hydrogen peroxide (H 2 O 2) in different
organelles and compartments. The suitability of H 2 O 2 as an intracellular signaling …

Hydrogen peroxide (H2O2), a by-product of a degenerative reaction of reactive oxygen
species in mammalian cells, has been examined in association with the pathology of …

Epithelial injury induces rapid recruitment of antimicrobial leukocytes to the wound site. In
zebrafish larvae, activation of the epithelial NADPH oxidase Duox at the wound margin is …