Background and Objectives: Periodontitis is marked by the destruction of alveolar bone.
Sclerostin (SOST) and dickkopf-1 (DKK-1) act as inhibitors of the Wingless-type (Wnt) …

Abstract Objective and Background Both periodontitis and osteoporosis are associated with
osteoclast‐related bone resorption. Bone metabolism is regulated by wingless‐type MMTV …

Aim: The purpose of this study was to measure the concentration of sclerostin in the gingival
crevicular fluid (GCF) before and after 1, 3, and 6 weeks of nonsurgical periodontal therapy …

Abstract Aim The regulation of Wnt‐β‐catenin signalling, which is crucial for osteoblast
differentiation and for bone resorption, is driven by critical inhibitors such as sclerostin …

Aim This study evaluated the levels of sclerostin (SOST) and Dickkopf (DKK)‐1 in the
chronic periodontitis (CP) associated with type 2 diabetes (DM) and/or smoking …

Background Statins are widely used for the treatment of hyperlipidemia. However, these
drugs have pleiotropic effects that can be promising for the prevention and treatment of oral …

Diabetes mellitus (DM) is a metabolic disease defined by hyperglycemia, which is
associated with periodontal disease and exerts an effect on bone metabolism. The aim of …

Background and Objectives: Wnt signaling leads to stimulation of osteoblasts and it reduces
osteoclastogenesis and bone resorption via the regulation of the osteprotegrin and receptor …

Background. Sclerostin, a glycoprotein, plays a key role in regulating bone mass. In this
study, sclerostin levels in the gingival crevicular fluid (GCF) were assessed in patients with …

Introduction and objective: Chronic periodontitis is the most common form of periodontal
disease. Progression of the disease is due to high levels of pro-inflammatory cytokines …