The success of vaccines is dependent on the generation and maintenance of immunological
memory. The immune system can remember previously encountered pathogens, and …

Recent advances in studies of immune memory in mice and humans have reinforced the
concept that memory B cells play a critical role in protection against repeated infections …

The successful establishment of humoral memory response depends on at least two layers
of defense. Pre‐existing protective antibodies secreted by long‐lived plasma cells act as a …

Surviving a single infection often results in lifelong immunity to the infecting pathogen. Such
protection is mediated, in large part, by two main B cell memory 'walls'—namely, long-lived …

Protection against pathogen re-infection is mediated, in large part, by two humoral cellular
compartments, namely, long-lived plasma cells and memory B cells. Recent data have …

Following an immune response two types of differentiated B cells persist in the memory pool:
plasma cells, which confer immediate protection by the secretion of specific antibodies; and …

The immune system can remember a previously experienced pathogen and can evoke an
enhanced response to reinfection that depends on memory lymphocyte populations. Recent …

Memory is a hallmark of immunity. Memory carried by antibodies is largely responsible for
protection against reinfection with most known acutely lethal infectious agents and is the …

Vaccine-induced memory B cell responses to evolving viruses like influenza A involve
activation of pre-existing immunity and generation of new responses. To define the …

We comprehensively review memory B cells (MBCs), covering the definition of MBCs and
their identities and subsets, how MBCs are generated, where they are localized, how they …