[PDF][PDF] The evolving landscape of HIV drug resistance diagnostics for expanding testing in resource-limited settings
Global scale-up of antiretroviral treatment has dramatically changed the prospects of
HIV/AIDS disease, rendering life-long chronic care and treatment a reality for millions of HIV …
HIV/AIDS disease, rendering life-long chronic care and treatment a reality for millions of HIV …
[HTML][HTML] HIV-1 drug resistance genotyping in resource limited settings: current and future perspectives in sequencing technologies
Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …
[HTML][HTML] Towards Next-Generation sequencing for HIV-1 Drug Resistance Testing in a clinical setting
CHY Teo, NHB Norhisham, OF Lee, S Png, CN Chai… - Viruses, 2022 - mdpi.com
The HIV genotypic resistance test (GRT) is a standard of care for the clinical management of
HIV/AIDS patients. In recent decades, population or Sanger sequencing has been the …
HIV/AIDS patients. In recent decades, population or Sanger sequencing has been the …
HIV-1 genotypic drug resistance testing: digging deep, reaching wide?
K Van Laethem, K Theys, AM Vandamme - Current opinion in virology, 2015 - Elsevier
Highlights•Technological innovations enable the global roll-out of drug resistance
surveillance.•Next-generation sequencing provides an answer for simultaneous resistance …
surveillance.•Next-generation sequencing provides an answer for simultaneous resistance …
[HTML][HTML] Are we ready for NGS HIV drug resistance testing? The second “winnipeg consensus” symposium
HIV drug resistance is a major global challenge to successful and sustainable antiretroviral
therapy. Next-generation sequencing (NGS)-based HIV drug resistance (HIVDR) assays …
therapy. Next-generation sequencing (NGS)-based HIV drug resistance (HIVDR) assays …
Update on antiretroviral drug resistance testing: combining laboratory technology with patient care.
JW Wilson - The AIDS reader, 2003 - europepmc.org
HIV drug resistance testing has been considered an emerging asset to modernized HIV
management. Despite the increased number of antiretroviral agents currently available …
management. Despite the increased number of antiretroviral agents currently available …
[HTML][HTML] Development and application of performance assessment criteria for next-generation sequencing-based HIV drug resistance assays
MG Becker, D Liang, B Cooper, Y Le, T Taylor, ER Lee… - Viruses, 2020 - mdpi.com
Next-generation sequencing (NGS)-based HIV drug resistance (HIVDR) assays outperform
conventional Sanger sequencing in scalability, sensitivity, and quantitative detection of …
conventional Sanger sequencing in scalability, sensitivity, and quantitative detection of …
[HTML][HTML] External quality assessment for next-generation sequencing-based HIV drug resistance testing: Unique requirements and challenges
Over the past decade, there has been an increase in the adoption of next generation
sequencing (NGS) technologies for HIV drug resistance (HIVDR) testing. NGS far outweighs …
sequencing (NGS) technologies for HIV drug resistance (HIVDR) testing. NGS far outweighs …
[HTML][HTML] Next-generation sequencing for HIV drug resistance testing: laboratory, clinical, and implementation considerations
Higher accessibility and decreasing costs of next generation sequencing (NGS), availability
of commercial kits, and development of dedicated analysis pipelines, have allowed an …
of commercial kits, and development of dedicated analysis pipelines, have allowed an …
An affordable HIV-1 drug resistance monitoring method for resource limited settings
J Manasa, S Danaviah, S Pillay, P Padayachee… - JoVE (Journal of …, 2014 - jove.com
HIV-1 drug resistance has the potential to seriously compromise the effectiveness and
impact of antiretroviral therapy (ART). As ART programs in sub-Saharan Africa continue to …
impact of antiretroviral therapy (ART). As ART programs in sub-Saharan Africa continue to …