Global scale-up of antiretroviral treatment has dramatically changed the prospects of
HIV/AIDS disease, rendering life-long chronic care and treatment a reality for millions of HIV …

Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …

The HIV genotypic resistance test (GRT) is a standard of care for the clinical management of
HIV/AIDS patients. In recent decades, population or Sanger sequencing has been the …

Highlights•Technological innovations enable the global roll-out of drug resistance
surveillance.•Next-generation sequencing provides an answer for simultaneous resistance …

HIV drug resistance is a major global challenge to successful and sustainable antiretroviral
therapy. Next-generation sequencing (NGS)-based HIV drug resistance (HIVDR) assays …

HIV drug resistance testing has been considered an emerging asset to modernized HIV
management. Despite the increased number of antiretroviral agents currently available …

Next-generation sequencing (NGS)-based HIV drug resistance (HIVDR) assays outperform
conventional Sanger sequencing in scalability, sensitivity, and quantitative detection of …

Over the past decade, there has been an increase in the adoption of next generation
sequencing (NGS) technologies for HIV drug resistance (HIVDR) testing. NGS far outweighs …

Higher accessibility and decreasing costs of next generation sequencing (NGS), availability
of commercial kits, and development of dedicated analysis pipelines, have allowed an …

HIV-1 drug resistance has the potential to seriously compromise the effectiveness and
impact of antiretroviral therapy (ART). As ART programs in sub-Saharan Africa continue to …