Progress in tumor-associated macrophage (TAM)-targeted therapeutics
C Ngambenjawong, HH Gustafson, SH Pun - Advanced drug delivery …, 2017 - Elsevier
As an essential innate immune population for maintaining body homeostasis and warding
off foreign pathogens, macrophages display high plasticity and perform diverse supportive …
off foreign pathogens, macrophages display high plasticity and perform diverse supportive …
[HTML][HTML] Targeting macrophages: a novel treatment strategy in solid tumors
M Liu, L Liu, Y Song, W Li, L Xu - Journal of Translational Medicine, 2022 - Springer
In the tumor microenvironment (TME), tumor-associated macrophages (TAMs) are the most
abundant immune cells, which act as a key regulator in tumorigenesis and progression …
abundant immune cells, which act as a key regulator in tumorigenesis and progression …
[HTML][HTML] Targeting tumor-associated macrophages for cancer treatment
M Li, L He, J Zhu, P Zhang, S Liang - Cell & bioscience, 2022 - Springer
Tumor-associated macrophages (TAMs) are abundant, nearly accounting for 30–50% of
stromal cells in the tumor microenvironment. TAMs exhibit an immunosuppressive M2-like …
stromal cells in the tumor microenvironment. TAMs exhibit an immunosuppressive M2-like …
[HTML][HTML] Targeting tumor-associated macrophages in cancer immunotherapy
AJ Petty, DH Owen, Y Yang, X Huang - Cancers, 2021 - mdpi.com
Simple Summary Tumor-associated macrophages (TAMs) coinhabit the tumor
microenvironment with cancer, immune, and stromal cells. They undermine the immune …
microenvironment with cancer, immune, and stromal cells. They undermine the immune …
Targeting tumor-associated macrophages as an antitumor strategy
N Cheng, X Bai, Y Shu, O Ahmad, P Shen - Biochemical pharmacology, 2021 - Elsevier
Tumor-associated macrophages (TAMs) are the most widely infiltrating immune cells in the
tumor microenvironment (TME). Clinically, the number of TAMs is closely correlated with …
tumor microenvironment (TME). Clinically, the number of TAMs is closely correlated with …
[HTML][HTML] Tumor-associated macrophages: A promising target for a cancer immunotherapeutic strategy
SY Zhang, XY Song, Y Li, LL Ye, Q Zhou… - Pharmacological …, 2020 - Elsevier
Macrophages, a type of myeloid immune cell, play essential roles in fighting against
pathogenic invasion and activating T cell-mediated adaptive immune responses. As a major …
pathogenic invasion and activating T cell-mediated adaptive immune responses. As a major …
[HTML][HTML] Harnessing tumor-associated macrophages as aids for cancer immunotherapy
Cancer immunotherapies that engage immune cells to fight against tumors are proving to be
powerful weapons in combating cancer and are becoming increasingly utilized in the clinics …
powerful weapons in combating cancer and are becoming increasingly utilized in the clinics …
Research trends in pharmacological modulation of tumor‐associated macrophages
N Wang, S Wang, X Wang, Y Zheng… - Clinical and …, 2021 - Wiley Online Library
As one of the most abundant immune cell populations in the tumor microenvironment (TME),
tumor‐associated macrophages (TAMs) play important roles in multiple solid malignancies …
tumor‐associated macrophages (TAMs) play important roles in multiple solid malignancies …
Targeting tumor‐associated macrophages: A potential treatment for solid tumors
Y Chen, H Jin, Y Song, T Huang, J Cao… - Journal of Cellular …, 2021 - Wiley Online Library
Tumor‐associated macrophages (TAMs) in solid tumors exert protumor activities by
releasing cytokines or growth factors into the tumor microenvironment. Increasing studies …
releasing cytokines or growth factors into the tumor microenvironment. Increasing studies …
[HTML][HTML] Targeting macrophages in cancer: from bench to bedside
AR Poh, M Ernst - Frontiers in oncology, 2018 - frontiersin.org
Macrophages are a major component of the tumor microenvironment and orchestrate
various aspects of immunity. Within tumors, macrophages can reversibly alter their endotype …
various aspects of immunity. Within tumors, macrophages can reversibly alter their endotype …