A promising novel target for anti-cancer therapy is the tumour vasculature. Both primary
tumour growth and the formation of metastasis depend on the establishment of new blood …

Angiogenesis—process of new blood-vessel growth from existing vasculature—is an
integral part of both normal developmental processes and numerous pathologies such as …

Angiogenesis is the outgrowth of new vessels from pre-existing ones. Tumour growth and
metastasis is dependent on angiogenesis and many stimulatory and inhibitory factors have …

Tumor cells cannot grow as a mass above 2 to 3 mm3 because diffusion is insufficient for
oxygen and glucose requirements, unless the tumor induces a blood supply. This …

Angiogenesis, the development of a new blood supply, is an essential process of tumour
growth and metastasis. Over the past few years, this has led to the consideration of the …

Cancer is a group of diseases with significant morbidity and mortality. In cancer cells, where
energy requirements are exceptionally high, angiogenesis, which is the sprouting of new …

Background: Angiogenesis is essential for tumour growth and development and since the
pioneering work of Judah Folkman several anti-angiogenic strategies have now been …

Inhibition of angiogenesis or preventing the outgrowth of new blood vessels towards a tumor
is one of the most promising areas of anticancer drug development. Several angiogenesis …

Angiogenesis has been described as one of the hallmarks of cancer, playing an essential
role in tumor growth, invasion, and metastasis. Antiangiogenic therapy was initially …

In 1971, Folkman proposed that tumors could be limited to very small sizes by blocking
angiogenesis. Angiogenesis is the generation of new blood vessels from pre-existing …