ContextMalignancies arising from the aerodigestive epithelium, including lung, head and
neck, and esophageal carcinomas, are the leading causes of cancer-related mortality …

Esophageal and gastric cancer incidence has been increasing worldwide. Most cases are
diagnosed in advanced stages, and current therapy has not been able to improve the …

Cancers of the esophagus and stomach present a major health burden worldwide. In the
past 30 years we have witnessed some interesting shifts in terms of epidemiology of …

Esophageal adenocarcinoma (EAC) is one of the fastest growing malignancies in the US.
The long-term survival of patients with this cancer remains poor; only 25% of patients …

The most common sites of malignancies in the aerodigestive tract include the lung, head
and neck and the esophagus. Esophageal adenocarcinomas (EA), esophageal squamous …

Background: Agents targeting the epidermal growth factor (EGFR)-mediated signaling
pathway are used in the treatment of various solid tumors, including lung, breast, pancreatic …

Epidermal growth factor receptor inhibitors in the treatment... : Current Opinion in Oncology
Epidermal growth factor receptor inhibitors in the treatment of lung cancer: reality and hopes …

Background The epidermal growth factor receptor (EGFR) pathway is important in tumor
growth, survival, and metastasis and is now the target of several therapeutic agents …

Purpose: At presentation, most cases of adenocarcinoma of the esophagus (ACE) are
inoperable. Although chemotherapy can prolong survival, patients eventually die as a result …

Esophagogastric cancer represents a significant global health problem, with most patients
presenting with advanced-stage disease and consequently with a poor prognosis …