Over the last years, repurposed agents have provided growing evidence of fast
implementation in oncology treatment such as certain antimalarial, anthelmintic, antibiotics …

Research on cancer therapies focuses on processes such as angiogenesis, cell signaling,
stemness, metastasis, and drug resistance and inflammation, all of which are influenced by …

Metabolic syndrome is associated with chronic diseases, including type 2 diabetes,
cardiovascular diseases, and cancer. This review summarizes the current evidence on the …

Metformin, a natural product from Galega officinalis, is an oral drug, now in the forefront of
the therapeutic management of type-2 diabetes mellitus. A series of clinical observations of …

This systematic review and meta-analysis is the first to evaluate the evidence for an
association between metformin use and cancer outcomes in patients undergoing treatment …

Metformin is widely used in the treatment of diabetes mellitus type 2 where it reduces insulin
resistance and diabetes-related morbidity and mortality. Population-based studies show that …

At the time of writing, a search in ClinicalTrials. gov yields six open studies evaluating the
efficacy and safety of treating cancer patients with the antidiabetic biguanide metformin. At …

Importance Preclinical and retrospective studies showed that β-blockers inhibit
angiogenesis and disrupt migration of melanoma cells via inhibition of noradrenaline …

Recent clinical evidence revealed that the use of beta-blockers such as propranolol, prior to
diagnosis or concurrently with chemotherapy, could increase relapse-free and overall …

How many lives have already been saved by the anti-cancer drug metformin? Inadvertently
perhaps, among the millions of type 2 diabetics with occult or known cancers and who have …