Mechanism for blockade of angiotensin subtype 1 receptors to lower plasma glucose in streptozotocin‐induced diabetic rats

P Chan, IM Liu, TF Tzeng, TL Yang… - Diabetes, Obesity and …, 2007 - Wiley Online Library
Aims: We investigated the mechanism (s) by which valsartan, a selective antagonist of
angiotensin subtype 1 (AT1) receptor, decreased plasma glucose in streptozotocin (STZ) …

Antihyperglycemic action of angiotensin II receptor antagonist, valsartan, in streptozotocin-induced diabetic rats

P Chan, KL Wong, IM Liu, TF Tzeng… - Journal of …, 2003 - journals.lww.com
Objectives In the present study, we use valsartan, a highly selective antagonist for
angiotensin 1 (AT 1) receptor subtype, to investigate the effect of AT 1 receptor on the …

Activation of imidazoline receptors in adrenal gland to lower plasma glucose in streptozotocin-induced diabetic rats

SL Hwang, IM Liu, TF Tzeng, JT Cheng - Diabetologia, 2005 - Springer
Aims/hypothesis The present study investigated the effect of agmatine, an endogenous
ligand of imidazoline receptors, on plasma glucose in streptozotocin-induced diabetic rats …

Novel mechanism for plasma glucose–lowering action of metformin in streptozotocin-induced diabetic rats

JT Cheng, CC Huang, IM Liu, TF Tzeng, CJ Chang - Diabetes, 2006 - Am Diabetes Assoc
To better understand the insulin-independent plasma glucose–lowering action of metformin,
we used streptozotocin (STZ)-induced diabetic rats to investigate the possible mechanisms …

Mediation of β-endorphin by ginsenoside Rh2 to lower plasma glucose in streptozotocin-induced diabetic rats

DM Lai, YK Tu, IM Liu, PF Chen, JT Cheng - Planta medica, 2006 - thieme-connect.com
We investigated the plasma glucose-lowering mechanism (s) of Rh2, a ginsenoside derived
from Panax ginseng, in rats with streptozotocin-induced diabetes (STZ-diabetic rats). After …

Release of β-endorphin by caffeic acid to lower plasma glucose in streptozotocin-induced diabetic rats

JT Cheng, IM Liu, TF Tzeng, WC Chen… - Hormone and …, 2003 - thieme-connect.com
The role of α 1A-adrenoceptors in the regulation of opioid secretion from the adrenal glands
of streptozotocin-induced diabetic rats (STZ-diabetic rats) was examined in an attempt to …

Serotonin enhances β-endorphin secretion to lower plasma glucose in streptozotocin-induced diabetic rats

TC Chi, YJ Ho, WP Chen, TL Chi, SS Lee, JT Cheng… - Life sciences, 2007 - Elsevier
Although serotonin, serotonin uptake inhibitors and serotonin precursors (including
tryptophan or 5-hydroxytryptophan) are known to have hypoglycemic action in rodents or …

Mediation of β-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats

IM Liu, WC Chen, JT Cheng - Journal of Pharmacology and Experimental …, 2003 - ASPET
We investigated the mechanism (s) by which isoferulic acid lowers plasma glucose levels in
streptozotocin-induced diabetic rats (STZ-diabetic rats). In STZ-diabetic rats, isoferulic acid …

Selective angiotensin II receptor antagonism reduces insulin resistance in obese Zucker rats

EJ Henriksen, S Jacob, TR Kinnick, MK Teachey… - …, 2001 - Am Heart Assoc
Effects of oral administration of the angiotensin II receptor antagonist (selective AT1-
subtype) irbesartan on glucose tolerance and insulin action on skeletal-muscle glucose …

Renal expression of angiotensin receptors in long-term diabetes and the effects of angiotensin type 1 receptor blockade

F Bonnet, R Candido, RM Carey, D Casley… - Journal of …, 2002 - journals.lww.com
Objective The aims of this study were to assess the renal expression of angiotensin type 1
(AT1) and type 2 (AT2) receptors in diabetic spontaneously hypertensive rats (SHR) and the …