Background Male testicular dysfunction is a considerable complication of anti-cancer
therapies, including chemotherapy and radiotherapy, partly due to the increased oxidative …

Background Modern societies face infertility as a global challenge. There are certain
environmental conditions and disorders that damage testicular tissue and may cause male …

Background Environmental pollution and infertility are two modern global challenges that
agonize personal and public health. The causal relationship between these two deserves …

Background Male infertility is a multifaceted issue that has gained scientific interest due to its
increasing rate. Studies have demonstrated that oxidative stress is involved in male infertility …

There is growing concern that some cytotoxic regimens for cancer adversely affect
spermatogenesis and male fertility. Increasing evidence demonstrated that melatonin has …

Background Ionizing radiations (IR) have widespread useful applications in our daily life;
however, they have unfavorable effects on reproductive health. Maintaining testicular health …

Infertility is a major global health issue and male factors account for half of all infertility
cases. One of the causes of male infertility is the loss of spermatogonial stem cells, which …

Testicular cancer is the most common cancer affecting men of reproductive age, and its
incidence is increasing steadily. A regimen of cisplatin (P), vinblastin (V) and bleomycin …

Cisplatin has the potential to cause kidney and reproductive organ injuries, prompting the
search for protective agents against cisplatin-induced toxicity. Melatonin, an antioxidant …

Abstract Melatonin (N-acetyl-5-methoxytryptamine), the main product of pineal gland in
vertebrates, is well known for its multifunctional role which has great influences on the …