Features of portal hypertension are associated with major adverse events in Fontan patients: the VAST study

RW Elder, NM McCabe, C Hebson, E Veledar… - International journal of …, 2013 - Elsevier
Background Chronic congestive hepatopathy is known to cause hepatic fibrosis and portal
hypertension in patients post-Fontan operation for single ventricle palliation. The clinical …

[HTML][HTML] Liver health in adults with Fontan circulation: a multicenter cross-sectional study

FM Wu, B Kogon, MG Earing, JA Aboulhosn… - The Journal of thoracic …, 2017 - Elsevier
Objectives Liver disease is an important contributor to morbidity and mortality in patients
after Fontan surgery. There has been no large-scale survey of liver health in this population …

Fontan circulation causes early, severe liver damage. Should we offer patients a tailored strategy?

G Agnoletti, G Ferraro, R Bordese, D Marini… - International Journal of …, 2016 - Elsevier
Abstract Background In patients with Fontan circulation, the liver is profoundly affected by
chronic venous stasis. Little is known about early hepatic changes in this population …

Portal and centrilobular hepatic fibrosis in Fontan circulation and clinical outcomes

FM Wu, MM Jonas, AR Opotowsky, A Harmon… - The Journal of Heart and …, 2015 - Elsevier
Background The Fontan operation redirects venous blood flow directly to the pulmonary
circulation in subjects with single ventricle anatomy. Congestive hepatopathy and cirrhosis …

Late hepatic complications after Fontan operation; non-invasive markers of hepatic fibrosis and risk factors

JS Baek, EJ Bae, JS Ko, GB Kim, BS Kwon, SY Lee… - Heart, 2010 - heart.bmj.com
Objective To identify the prevalence, clinical characteristics, risk factors of hepatic
complications after a Fontan operation. Methods This was a cross-sectional study of 139 …

Hemodynamic phenotype of the failing Fontan in an adult population

CL Hebson, NM McCabe, RW Elder, WT Mahle… - The American journal of …, 2013 - Elsevier
Fontan failure can occur even with normal systolic ventricular function and often in the
context of significant liver disease. We hypothesized that Fontan failure is hemodynamically …

Clinical outcomes of adult Fontan-associated liver disease and combined heart-liver transplantation

MJ Lewis, LC Reardon, J Aboulhosn, C Haeffele… - Journal of the American …, 2023 - jacc.org
Abstract Background The impact of Fontan-associated liver disease (FALD) on post-
transplant mortality and indications for combined heart-liver transplant (CHLT) in adult …

[HTML][HTML] Fontan-associated liver disease: A review

TT Gordon-Walker, K Bove, G Veldtman - Journal of cardiology, 2019 - Elsevier
The Fontan procedure has led to increased long-term survival of patients with single
ventricle congenital heart disease. Hemodynamic changes associated with the Fontan …

Haemodynamic profiles in adult Fontan patients: associated haemodynamics and prognosis

WR Miranda, BA Borlaug, DJ Hagler… - European journal of …, 2019 - Wiley Online Library
Aims The Fontan operation is associated with significant long‐term morbidity and mortality,
posing challenges in management. No haemodynamic classification has been established …

Transvenous hepatic biopsy in stable Fontan patients undergoing cardiac catheterization

WN Evans, BJ Winn, NS Yumiaco, A Galindo… - Pediatric …, 2014 - Springer
Liver pathology complicates Fontan palliation. Previous reports established that both hepatic
sinusoidal and portal fibrosis occur in patients after Fontan procedures. Past studies …