The role of exosome-mediated mitophagy in the crosstalk between hepatocytes (HCs) and
hepatic stellate cells (HSCs) in metabolic-associated fatty liver disease (MAFLD) remains …

Background & Aims Liver fibrosis arises from long-term chronic liver injury, accompanied by
an accelerated wound healing response with interstitial accumulation of extracellular matrix …

Lipotoxic hepatocyte-derived exosomal miR-1297 promotes hepatic stellate cell activation
through the PTEN signaling pathway in metabolic-associated fatty liver disease - PMC Back to …

Background & Aims Accumulating evidence has indicated the presence of mature
microRNAs (miR) in the nucleus, but their effects on steatohepatitis remain elusive. We have …

Activation of hepatic stellate cell (HSC), which is the main source of extracellular matrix,
plays a pivotal role in liver fibrogenesis. Autophagy of hepatic stellate cell has been recently …

Hepatic macrophages can be activated by many factors such as gut-derived bacterial
components and factors released from damaged hepatocytes. Macrophage polarization …

Abstract Background and Aims Non-alcoholic fatty liver disease (NAFLD) and its
complications has become an expanding health problem worldwide with limited therapeutic …

Liver fibrosis is a severe stage of nonalcoholic fatty liver disease (NAFLD), which is closely
associated with the activation of hepatic stellate cells (HSCs) and their interaction with …

Aim To investigate the association of serum exosomes miR-574-5p with liver fibrosis, and
explore the effect and mechanism of serum exosomes on HSC activation. Materials and …

To investigate the role of miR-122 in the development and regression of non-alcoholic fatty
liver disease (NAFLD) in vitro, we used multicellular 3D human liver organoids developed in …