Background. The mechanism for pain associated with intravenous administration of propofol
is believed to be related to the release of nitric oxide. We hypothesized that pain following …

Background: Pain at the site of intravenous injection of propofol is a common clinical finding.
This double‐blind, randomized cross‐over study was designed to evaluate whether venous …

Objective: Propofol, an intravenous (IV) anesthetic, can irritate the skin, mucous membrane,
and venous intima. The main drawback is the pain on injecting it. We compared the …

Purpose Pain on propofol injection is a common adverse effect. This study examined the
effect of a combination of nitroglycerin and lidocaine on pain during propofol injection …

Background Direct stimulation of the afferent nerve endings in the venous endothelium is
one explanation of propofol injection pain. Previous studies found that ondansetron can also …

Objective Pain is a well recognised complication of propofol injection. The purpose of this
study was to compare the efficacy of flurbiprofen, lidocaine and a combination of the two in …

Background: Pain on injection is a common adverse effect with propofol used for general
anesthesia. Objectives: The aims of this study were to evaluate the analgesic effect of …

JUSTIFICATIVA E OBJETIVOS: Foi realizado estudo duplamente encoberto, aleatório, para
avaliar a eficácia do tratamento prévio, por via venosa, com lidocaína, paracetamol …

Propofol causes pain on intravenous injection in 28 to 90% of patients. A number of
techniques have been tried to minimize propofol-induced pain, with variable results. In a …

Background: The incidence of propofol injection pain during induction of general anesthesia
varies from 28% to 90%. This prospective, randomized, double-blind, placebo-controlled …