DNA mismatch repair: molecular mechanism, cancer, and ageing

P Hsieh, K Yamane - Mechanisms of ageing and development, 2008 - Elsevier
DNA mismatch repair (MMR) proteins are ubiquitous players in a diverse array of important
cellular functions. In its role in post-replication repair, MMR safeguards the genome …

New insights into the mechanism of DNA mismatch repair

GX Reyes, TT Schmidt, RD Kolodner, H Hombauer - Chromosoma, 2015 - Springer
The genome of all organisms is constantly being challenged by endogenous and
exogenous sources of DNA damage. Errors like base: base mismatches or small insertions …

DNA mismatch repair and its many roles in eukaryotic cells

D Liu, G Keijzers, LJ Rasmussen - Mutation Research/Reviews in Mutation …, 2017 - Elsevier
DNA mismatch repair (MMR) is an important DNA repair pathway that plays critical roles in
DNA replication fidelity, mutation avoidance and genome stability, all of which contribute …

DNA mismatch repair and genetic instability

BD Harfe, S Jinks-Robertson - Annual review of genetics, 2000 - annualreviews.org
▪ Abstract Mismatch repair (MMR) systems play a central role in promoting genetic stability
by repairing DNA replication errors, inhibiting recombination between non-identical DNA …

Mammalian DNA mismatch repair

AB Buermeyer, SM Deschênes, SM Baker… - Annual review of …, 1999 - annualreviews.org
▪ Abstract DNA mismatch repair (MMR) is one of multiple replication, repair, and
recombination processes that are required to maintain genomic stability in prokaryotes and …

Mechanisms and functions of DNA mismatch repair

GM Li - Cell research, 2008 - nature.com
DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role
in maintaining genomic stability. The specificity of MMR is primarily for base-base …

[HTML][HTML] Constitutional mismatch repair-deficiency: current problems and emerging therapeutic strategies

M Abedalthagafi - Oncotarget, 2018 - ncbi.nlm.nih.gov
Constitutional mismatch repair-deficiency: current problems and emerging therapeutic
strategies - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Functional interactions and signaling properties of mammalian DNA mismatch repair proteins

A Bellacosa - Cell Death & Differentiation, 2001 - nature.com
The mismatch repair (MMR) system promotes genomic fidelity by repairing base-base
mismatches, insertion-deletion loops and heterologies generated during DNA replication …

DNA mismatch repair: molecular mechanisms and biological function

MJ Schofield, P Hsieh - Annual Reviews in Microbiology, 2003 - annualreviews.org
▪ Abstract DNA mismatch repair (MMR) guards the integrity of the genome in virtually all
cells. It contributes about 1000-fold to the overall fidelity of replication and targets mispaired …

Exploiting DNA mismatch repair deficiency as a therapeutic strategy

D Guillotin, SA Martin - Experimental cell research, 2014 - Elsevier
Abstract The DNA Mismatch repair (MMR) pathway is critical for the maintenance of genomic
stability. It is primarily responsible for the recognition and repair of mismatches that occur …