The spread of carbapenemase producers in Enterobacteriaceae has now been identified
worldwide. Three main carbapenemases have been reported; they belong to three classes …

Carbapenemases increasingly have been reported in Enterobacteriaceae in the past 10
years. Klebsiella pneumoniae carbapenemases have been reported in the United States …

Plasmid-acquired carbapenemases in Enterobacteriaceae, which were first discovered in
Europe in the 1990s, are now increasingly being identified at an alarming rate. Although …

Emergence and dissemination of Enterobacteriaceae isolates harboring carbapenemases
in various geographic regions represents a significant threat to the management of …

Acquired carbapenemases are emerging resistance determinants in Gram-negative
pathogens, including Enterobacteriaceae, Pseudomonas aeruginosa and other Gram …

The spread of carbapenem-hydrolysing β-lactamases in Enterobacteriaceae is becoming a
major public health issue. These β-lactamases hydrolyse almost all β-lactams, are plasmid …

Background Gaps in the diagnostic capacity and heterogeneity of national surveillance and
reporting standards in Europe make it difficult to contain carbapenemase-producing …

Background Carbapenemase-producing enterobacteriaceae (CPE) are a major threat for
severely ill patients. However, only limited data on the epidemiology and on evidence-based …

Sir, A large number of acquired carbapenemases have been identified and characterized
among Gram-negative pathogens. These diverse enzymes, belonging to either molecular …

To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the
Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of …