[HTML][HTML] Genomic or non-genomic? A question about the pleiotropic roles of vitamin D in inflammatory-based diseases
MF Holick, L Mazzei, S García Menéndez… - Nutrients, 2023 - mdpi.com
Vitamin D (vit D) is widely known for its role in calcium metabolism and its importance for the
bone system. However, various studies have revealed a myriad of extra-skeletal functions …
bone system. However, various studies have revealed a myriad of extra-skeletal functions …
[HTML][HTML] Vitamin D in inflammatory diseases
TK Wöbke, BL Sorg, D Steinhilber - Frontiers in physiology, 2014 - frontiersin.org
Changes in vitamin D serum levels have been associated with inflammatory diseases, such
as inflammatory bowel disease (IBD), rheumatoid arthritis, systemic lupus erythematosus …
as inflammatory bowel disease (IBD), rheumatoid arthritis, systemic lupus erythematosus …
Vitamin D as a principal factor in mediating rheumatoid arthritis‐derived immune response
Rheumatoid arthritis (RA) is a systemic multifactorial autoimmune disorder. The interactions
between diverse environmental and genetic factors lead to the onset of this complex …
between diverse environmental and genetic factors lead to the onset of this complex …
[HTML][HTML] Vitamin D in autoimmunity: molecular mechanisms and therapeutic potential
W Dankers, EM Colin, JP Van Hamburg… - Frontiers in …, 2017 - frontiersin.org
Over the last three decades, it has become clear that the role of vitamin D goes beyond the
regulation of calcium homeostasis and bone health. An important extraskeletal effect of …
regulation of calcium homeostasis and bone health. An important extraskeletal effect of …
Vitamin-D in the immune system: genomic and non-genomic actions
AI Trochoutsou, V Kloukina, K Samitas… - Mini reviews in …, 2015 - ingentaconnect.com
More than thirty years ago functions of vitamin D other than its beneficial effects on calcium
homeostasis and bone metabolism have been identified, mainly in relation to its …
homeostasis and bone metabolism have been identified, mainly in relation to its …
[HTML][HTML] Vitamin D: an overview of gene regulation, ranging from metabolism to genomic effects
G Voltan, M Cannito, M Ferrarese, F Ceccato… - Genes, 2023 - mdpi.com
Vitamin D is a pro-hormone characterized by an intricate metabolism and regulation. It is
well known for its role in calcium and phosphate metabolism, and in bone health. However …
well known for its role in calcium and phosphate metabolism, and in bone health. However …
[HTML][HTML] immune-modulatory effects of vitamin D
SM Zughaier, E Lubberts, A Bener - Frontiers in immunology, 2020 - frontiersin.org
Vitamin D plays an essential role in bone development. However, recent studies are
beginning to uncover its role as a modulator of the immune system (1). Several reports have …
beginning to uncover its role as a modulator of the immune system (1). Several reports have …
[HTML][HTML] A review of the critical role of vitamin D axis on the immune system
In recent years, the physiological and molecular functions of vitamin D (Vit-D) have been
deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal …
deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal …
[HTML][HTML] Can we translate vitamin D immunomodulating effect on innate and adaptive immunity to vaccine response?
PO Lang, R Aspinall - Nutrients, 2015 - mdpi.com
Vitamin D (VitD), which is well known for its classic role in the maintenance of bone mineral
density, has now become increasingly studied for its extra-skeletal roles. It has an important …
density, has now become increasingly studied for its extra-skeletal roles. It has an important …
[HTML][HTML] VDR gene single nucleotide polymorphisms and autoimmunity: a narrative review
C Agliardi, FR Guerini, E Bolognesi, M Zanzottera… - Biology, 2023 - mdpi.com
Simple Summary The pathogenesis of autoimmune diseases etiology is still mostly unclear
and probably arises from an interplay between common/rare genetic variants and …
and probably arises from an interplay between common/rare genetic variants and …