Lung surfactant: Function and composition in the context of development and respiratory physiology

W Bernhard - Annals of Anatomy-Anatomischer Anzeiger, 2016 - Elsevier
Lung surfactant is a complex with a unique phospholipid and protein composition. Its
specific function is to reduce surface tension at the pulmonary air–liquid interface. The …

Understanding the principle biophysics concepts of pulmonary surfactant in health and disease

C Autilio, J Pérez-Gil - Archives of Disease in Childhood-Fetal and …, 2019 - fn.bmj.com
Pulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate
structure of mammalian alveoli along with successive compression-expansion respiratory …

Pulmonary surfactant in health and human lung diseases: state of the art

M Griese - European Respiratory Journal, 1999 - Eur Respiratory Soc
Pulmonary surfactant is a complex and highly surface active material composed of lipids and
proteins which is found in the fluid lining the alveolar surface of the lungs. Surfactant …

Metabolic and developmental aspects of the pulmonary surfactant system

M Post, LMG Van Golde - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1988 - Elsevier
The mechanical stability of the alveoli, the gasexchanging units of the lung, is highly
dependent upon the surface-active material that lines the alveolar surfaces. This complex …

[HTML][HTML] Pulmonary surfactant: functions and molecular composition

J Goerke - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 1998 - Elsevier
This review briefly notes recent findings important for understanding the surface mechanical
functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are …

Lung surfactant: how it does and does not work

AD Bangham - Lung, 1987 - Springer
Earlier analyses of the physical chemistry of lung surfactant (LS) are rejected on the grounds
that the definition of surface tension is not complied with. Furthermore, with 1 or 2 exceptions …

[引用][C] Regulation of pulmonary surfactant secretion and clearance

JR Wright, LG Dobbs - Annual review of physiology, 1991 - annualreviews.org
Pulmonary surfactant functions in the lungs at the interface between the air and the liquid
layer that covers the epithelial surface. Pulmonary surfactant is functionally, chemically, and …

Pulmonary surfactant: the key to the evolution of air breathing

CB Daniels, S Orgeig - Physiology, 2003 - journals.physiology.org
Pulmonary surfactant controls the surface tension at the air-liquid interface within the lung.
This system had a single evolutionary origin that predates the evolution of the vertebrates …

An overview of pulmonary surfactant in the neonate: genetics, metabolism, and the role of surfactant in health and disease

PO Nkadi, TA Merritt, DAM Pillers - Molecular genetics and metabolism, 2009 - Elsevier
Pulmonary surfactant is a complex mixture of phospholipids (PL) and proteins (SP) that
reduce surface tension at the air–liquid interface of the alveolus. It is made up of about 70 …

Pulmonary surfactant in birds: coping with surface tension in a tubular lung

W Bernhard, A Gebert, G Vieten… - American Journal …, 2001 - journals.physiology.org
As birds have tubular lungs that do not contain alveoli, avian surfactant predominantly
functions to maintain airflow in tubes rather than to prevent alveolar collapse. Consequently …