Adsorption of enzymes on solid surfaces may lead to conformational changes that reduce
their catalytic conversion activity and are thus detrimental to the efficiency of biotechnology …

Circular dichroism (CD) spectroscopy is one of the few experimental techniques sensitive to
the structural changes that peptides undergo when they adsorb on inorganic material …

Successfully immobilizing functional proteins on inorganic surfaces has long been a
challenge to the biophysics and bioengineering communities. This is due, in part, to a lack of …

The adsorption of α-chymotrypsin and hen egg white lysozyme on amorphous silica is
studied by molecular dynamics (MD) simulations in comparison with adsorption …

A central paradigm that underpins our understanding of the interaction of proteins with solid
surfaces is that protein adsorption leads to changes in secondary structure. The bound …

Protein adsorption on surfaces is used in analytical tools as an immobilization mean to trap
the analyte to be detected. However, protein adsorption can lead to a conformational …

In order to understand fundamental interactions at the interface between immobilized
enzymes and ceramic supports, the authors compare the adsorption features of …

Understanding the relationship between the amino acid sequence of a protein and its
unique, compact 3D structure is one of the grand challenges in molecular biophysics. One …

The change in the secondary structure of T4 lysozyme upon adsorption to silica particles
was studied with circular dichroism. Two different mutants of the protein along with the wild …

Silica nanostructures are biologically available and find wide applications for drug delivery,
catalysts, separation processes, and composites. However, specific adsorption of …