[HTML][HTML] Tyrosinase inhibitors naturally present in plants and synthetic modifications of these natural products as anti-melanogenic agents: a review
Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …
In the current review, different chemical derivatives are explored which have been used as …
Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future
YJ Kim, H Uyama - Cellular and molecular life sciences CMLS, 2005 - Springer
Tyrosinase is known to be a key enzyme in melanin biosynthesis, involved in determining
the color of mammalian skin and hair. Various dermatological disorders, such as melasma …
the color of mammalian skin and hair. Various dermatological disorders, such as melasma …
An updated organic classification of tyrosinase inhibitors on melanin biosynthesis
CY Chen, LC Lin, WF Yang, J Bordon… - Current Organic …, 2015 - ingentaconnect.com
Tyrosinase (EC 1.14. 18.1) is known to be the rate-limiting enzyme responsible for
catalyzing the first two steps in the synthesis of melanin pigments that determine the coloring …
catalyzing the first two steps in the synthesis of melanin pigments that determine the coloring …
Advances in the tyrosinase inhibitors from plant source
Tyrosinase is a multifunctional copper-containing oxidase which catalyses the oxidation of
tyrosine to produce melanin. The alteration in melanin biosynthesis occurs in many …
tyrosine to produce melanin. The alteration in melanin biosynthesis occurs in many …
Validation of medicinal herbs for anti-tyrosinase potential
Tyrosinase is a key regulatory multifunctional enzyme containing copper that is responsible
for the biosynthesis of melanin that determines the color of the skin. Accumulation of …
for the biosynthesis of melanin that determines the color of the skin. Accumulation of …
[HTML][HTML] Tyrosinase Inhibitors: A Perspective
MA Baber, CM Crist, NL Devolve, JD Patrone - Molecules, 2023 - mdpi.com
Due to its integral role in the biosynthesis of melanin in all kingdoms of life, tyrosinase has
become an extremely important target for inhibition in several sectors of research including …
become an extremely important target for inhibition in several sectors of research including …
Recent advances in the design and discovery of synthetic tyrosinase inhibitors
J Li, L Feng, L Liu, F Wang, L Ouyang, L Zhang… - European Journal of …, 2021 - Elsevier
Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …
Hydroxyl substituted benzoic acid/cinnamic acid derivatives: Tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies
The inhibition of tyrosinase is an established strategy for treating hyperpigmentation. Our
previous findings demonstrated that cinnamic acid and benzoic acid scaffolds can be …
previous findings demonstrated that cinnamic acid and benzoic acid scaffolds can be …
A comprehensive review on tyrosinase inhibitors
S Zolghadri, A Bahrami, MT Hassan Khan… - Journal of enzyme …, 2019 - Taylor & Francis
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …
[HTML][HTML] Heterocyclic compounds as synthetic tyrosinase inhibitors: recent advances
Tyrosinase is a copper-containing enzyme which is widely distributed in nature (eg, bacteria,
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …
mammals, fungi) and involved in two consecutive steps of melanin biosynthesis. In humans …
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