Antisense transcripts and antisense protein: a new perspective on human immunodeficiency virus type 1
J Savoret, JM Mesnard, A Gross, N Chazal - Frontiers in Microbiology, 2021 - frontiersin.org
It was first predicted in 1988 that there may be an Open Reading Frame (ORF) on the
negative strand of the Human Immunodeficiency Virus type 1 (HIV-1) genome that could …
negative strand of the Human Immunodeficiency Virus type 1 (HIV-1) genome that could …
The HIV-1 antisense gene ASP: the new kid on the block
Viruses have developed incredibly creative ways of making a virtue out of necessity,
including taking full advantage of their small genomes. Indeed, viruses often encode …
including taking full advantage of their small genomes. Indeed, viruses often encode …
Concomitant emergence of the antisense protein gene of HIV-1 and of the pandemic
E Cassan, AM Arigon-Chifolleau… - Proceedings of the …, 2016 - National Acad Sciences
Recent experiments provide sound arguments in favor of the in vivo expression of the
AntiSense Protein (ASP) of HIV-1. This putative protein is encoded on the antisense strand …
AntiSense Protein (ASP) of HIV-1. This putative protein is encoded on the antisense strand …
Reviving an old HIV-1 gene: the HIV-1 antisense protein
C Torresilla, JM Mesnard, B Barbeau - Current HIV research, 2015 - ingentaconnect.com
The existence of an HIV-1 protein translated from an antisense transcript was suggested
over 25 years ago. However, this Antisense Protein (ASP) gene has still not been completely …
over 25 years ago. However, this Antisense Protein (ASP) gene has still not been completely …
The HIV-1 antisense protein ASP is a transmembrane protein of the cell surface and an integral protein of the viral envelope
The negative strand of HIV-1 encodes a highly hydrophobic antisense protein (ASP) with no
known homologs. The presence of humoral and cellular immune responses to ASP in HIV-1 …
known homologs. The presence of humoral and cellular immune responses to ASP in HIV-1 …
A pilot study of the humoral response against the antisense protein (ASP) in HIV-1-infected patients
J Savoret, N Chazal, JP Moles, E Tuaillon… - Frontiers in …, 2020 - frontiersin.org
The existence of an antisense Open Reading Frame (ORF) that encodes a putative
AntiSense Protein (ASP) on the proviral genome of Human Immunodeficiency Virus type 1 …
AntiSense Protein (ASP) on the proviral genome of Human Immunodeficiency Virus type 1 …
Immunolocalization studies of an antisense protein in HIV-1-infected cells and viral particles
S Briquet, C Vaquero - Virology, 2002 - Elsevier
The minus DNA strand of HIV-1 presents an open reading frame that is complementary to
the HIV-1 envelope messenger, is highly conserved among HIV-1 isolates, and may encode …
the HIV-1 envelope messenger, is highly conserved among HIV-1 isolates, and may encode …
HIV-1-encoded antisense RNA suppresses viral replication for a prolonged period
M Kobayashi-Ishihara, M Yamagishi, T Hara… - Retrovirology, 2012 - Springer
Background Recent evidence proposes a novel concept that mammalian natural antisense
RNAs play important roles in cellular homeostasis by regulating the expression of several …
RNAs play important roles in cellular homeostasis by regulating the expression of several …
Detection of antisense protein (ASP) RNA transcripts in individuals infected with human immunodeficiency virus type 1 (HIV-1)
A Mancarella, FA Procopio, T Achsel… - Journal of General …, 2019 - microbiologyresearch.org
The detection of antisense RNA is hampered by reverse transcription (RT) non-specific
priming, due to the ability of RNA secondary structures to prime RT in the absence of specific …
priming, due to the ability of RNA secondary structures to prime RT in the absence of specific …
Creation of the HIV-1 antisense gene asp coincided with the emergence of the pandemic group M and is associated with faster disease progression
A Pavesi, F Romerio - Microbiology Spectrum, 2024 - Am Soc Microbiol
Despite being first identified more than three decades ago, the antisense gene asp of HIV-1
remains an enigma. asp is present uniquely in pandemic (group M) HIV-1 strains, and it is …
remains an enigma. asp is present uniquely in pandemic (group M) HIV-1 strains, and it is …