Background The present study was to detect the association of single nucleotide
polymorphism (SNP) in the breast susceptibility gene 2 (BRCA2) and the risk of coronary …

Background Ischaemic stroke is a common disorder with genetic and environmental
components contributing to overall risk. Atherothromboembolic abnormalities, which play a …

Background Atherosclerosis shares common pathogenic features with myocardial infarction
(MI) and ischemic stroke. BRCA-1 associated protein (BRAP), a newly identified risk gene …

Background ATP binding cassette transporters ABCA1 and ABCG1 play a crucial role in
cholesterol efflux and reverse cholesterol transport (RCT), thereby rendering ischemic stroke …

Background Germline mutations of BRCA1/2 are associated with hereditary breast and
ovarian cancer. Recent data suggests excess mortality in mutation carriers beyond that …

A single nucleotide polymorphism (SNP) rs1122608 on chromosome 19p13. 2 and in the
BRG1/SMARCA4 gene was previously associated with coronary artery disease (CAD). CAD …

Background: Our previous studies have showed that the rs5888 single nucleotide
polymorphism (SNP) in Scavenger receptor class B type 1 (SCARB1) gene is associated …

Our previous studies identified nine genes and chromosomal region 3q28 as susceptibility
loci for myocardial infarction, ischemic stroke or chronic kidney disease by genome‑wide or …

The single nucleotide polymorphisms (SNPs) related to both coronary heart disease (CHD)
and ischemic stroke (IS) in Chinese individuals have not been identified definitely. This …

Background: Genome-wide association studies have identified single-nucleotide
polymorphisms that are associated with an increased risk of stroke. We sought to determine …