Mutation-independent proteomic signatures of pathological progression in murine models of Duchenne muscular dystrophy
TLE van Westering, HJ Johansson, B Hanson… - Molecular & Cellular …, 2020 - ASBMB
The absence of the dystrophin protein in Duchenne muscular dystrophy (DMD) results in
myofiber fragility and a plethora of downstream secondary pathologies. Although a variety of …
myofiber fragility and a plethora of downstream secondary pathologies. Although a variety of …
Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is caused by genetic deficiency of dystrophin and
characterized by massive structural and functional changes of skeletal muscle tissue …
characterized by massive structural and functional changes of skeletal muscle tissue …
Multiomics analysis of the mdx/mTR mouse model of Duchenne muscular dystrophy
DW Van Pelt, YA Kharaz, DC Sarver… - Connective Tissue …, 2021 - Taylor & Francis
ABSTRACT Purpose/Aim Duchenne muscular dystrophy (DMD) is a progressive
neuromuscular disease characterized by extensive muscle weakness. Patients with DMD …
neuromuscular disease characterized by extensive muscle weakness. Patients with DMD …
Mass spectrometry‐based protein analysis to unravel the tissue pathophysiology in Duchenne muscular dystrophy
SJ Carr, RP Zahedi, H Lochmüller… - PROTEOMICS–Clinical …, 2018 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is a genetic muscle wasting condition with limited
treatment options available and is caused by the lack of dystrophin. However …
treatment options available and is caused by the lack of dystrophin. However …
[PDF][PDF] Gene expression profiling of Duchenne muscular dystrophy reveals characteristics along disease progression
LJ Tian, JH Cao, XQ Deng, CL Zhang, T Qian… - Genet. Mol …, 2014 - geneticsmr.com
Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy with
no cure currently available. In this study, using two microarray data sets obtained from the …
no cure currently available. In this study, using two microarray data sets obtained from the …
Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy
Y Hathout, E Brody, PR Clemens… - Proceedings of the …, 2015 - National Acad Sciences
Serum biomarkers in Duchenne muscular dystrophy (DMD) may provide deeper insights
into disease pathogenesis, suggest new therapeutic approaches, serve as acute read-outs …
into disease pathogenesis, suggest new therapeutic approaches, serve as acute read-outs …
Gene expression profiling of Duchenne muscular dystrophy skeletal muscle
JN Haslett, D Sanoudou, AT Kho, M Han, RR Bennett… - Neurogenetics, 2003 - Springer
The primary cause of Duchenne muscular dystrophy (DMD) is a mutation in the dystrophin
gene, leading to absence of the corresponding protein, disruption of the dystrophin …
gene, leading to absence of the corresponding protein, disruption of the dystrophin …
Proteome Profiling of the Dystrophic mdx Mice Diaphragm
O Mucha, M Myszka, P Podkalicka, B Świderska… - Biomolecules, 2023 - mdpi.com
Mdx mice with a spontaneous mutation in exon 23 of the Dmd gene represent the most
common model to investigate the pathophysiology of Duchenne muscular dystrophy (DMD) …
common model to investigate the pathophysiology of Duchenne muscular dystrophy (DMD) …
Simultaneous Pathoproteomic Evaluation of the Dystrophin-Glycoprotein Complex and Secondary Changes in the mdx-4cv Mouse Model of Duchenne Muscular …
In skeletal muscle, the dystrophin-glycoprotein complex forms a membrane-associated
assembly of relatively low abundance, making its detailed proteomic characterization in …
assembly of relatively low abundance, making its detailed proteomic characterization in …
[HTML][HTML] The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy
JCW Hildyard, DO Riddell, RCM Harron… - Wellcome Open …, 2022 - ncbi.nlm.nih.gov
Background: Animal models of Duchenne muscular dystrophy (DMD) are essential to study
disease progression and assess efficacy of therapeutic intervention, however dystrophic …
disease progression and assess efficacy of therapeutic intervention, however dystrophic …