A model 450 million years in the making: zebrafish and vertebrate immunity
SA Renshaw, NS Trede - Disease models & mechanisms, 2012 - journals.biologists.com
Since its first splash 30 years ago, the use of the zebrafish model has been extended from a
tool for genetic dissection of early vertebrate development to the functional interrogation of …
tool for genetic dissection of early vertebrate development to the functional interrogation of …
Host-pathogen interactions made transparent with the zebrafish model
The zebrafish holds much promise as a high-throughput drug screening model for immune-
related diseases, including inflammatory and infectious diseases and cancer. This is due to …
related diseases, including inflammatory and infectious diseases and cancer. This is due to …
Immunology and zebrafish: spawning new models of human disease
ND Meeker, NS Trede - Developmental & Comparative Immunology, 2008 - Elsevier
The zebrafish has emerged as a powerful new vertebrate model of human disease. Initially
prominent in developmental biology, the zebrafish has now been adopted into varied fields …
prominent in developmental biology, the zebrafish has now been adopted into varied fields …
[HTML][HTML] Pathogen recognition and activation of the innate immune response in zebrafish
The zebrafish has proven itself as an excellent model to study vertebrate innate immunity. It
presents us with possibilities for in vivo imaging of host-pathogen interactions which are …
presents us with possibilities for in vivo imaging of host-pathogen interactions which are …
[PDF][PDF] The use of zebrafish to understand immunity
For decades immunologists have relied heavily on the mouse model for their experimental
designs. With the realization of the important role innate immunity plays in orchestrating …
designs. With the realization of the important role innate immunity plays in orchestrating …
Determining macrophage versus neutrophil contributions to innate immunity using larval zebrafish
EE Rosowski - Disease models & mechanisms, 2020 - journals.biologists.com
The specific roles of the two major innate immune cell types–neutrophils and macrophages–
in response to infection and sterile inflammation are areas of great interest. The larval …
in response to infection and sterile inflammation are areas of great interest. The larval …
Zebrafish: model for the study of inflammation and the innate immune response to infectious diseases
B Novoa, A Figueras - Current topics in innate immunity II, 2012 - Springer
The zebrafish (Danio rerio) has been extensively used in biomedical research as a model to
study vertebrate development and hematopoiesis and recently, it has been adopted into …
study vertebrate development and hematopoiesis and recently, it has been adopted into …
[HTML][HTML] The zebrafish as a model to study intestinal inflammation
S Brugman - Developmental & Comparative Immunology, 2016 - Elsevier
Starting out as a model for developmental biology, during the last decade, zebrafish have
also gained the attention of the immunologists and oncologists. Due to its small size, high …
also gained the attention of the immunologists and oncologists. Due to its small size, high …
Host–microbe interactions in the developing zebrafish
M Kanther, JF Rawls - Current opinion in immunology, 2010 - Elsevier
The amenability of the zebrafish to in vivo imaging and genetic analysis has fueled
expanded use of this vertebrate model to investigate the molecular and cellular foundations …
expanded use of this vertebrate model to investigate the molecular and cellular foundations …
[HTML][HTML] Feed, microbiota, and gut immunity: using the zebrafish model to understand fish health
Aquafeed companies aim to provide solutions to the various challenges related to nutrition
and health in aquaculture. Solutions to promote feed efficiency and growth, as well as …
and health in aquaculture. Solutions to promote feed efficiency and growth, as well as …