Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa

C Winstanley, MGI Langille, JL Fothergill… - Genome …, 2009 - genome.cshlp.org
Pseudomonas aeruginosa isolates have a highly conserved core genome representing up
to 90% of the total genomic sequence with additional variable accessory genes, many of …

Genomic islands of Pseudomonas aeruginosa

SE Battle, J Rello, AR Hauser - FEMS microbiology letters, 2009 - academic.oup.com
Key to Pseudomonas aeruginosa's ability to thrive in a diversity of niches is the presence of
numerous genomic islands that confer adaptive traits upon individual strains. We reasoned …

Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools

L Freschi, C Bertelli, J Jeukens… - FEMS microbiology …, 2018 - academic.oup.com
Pseudomonas aeruginosa is an important opportunistic pathogen, especially in the context
of infections of cystic fibrosis (CF). In order to facilitate coordinated study of this pathogen, an …

The effect of a bacteriophage on diversification of the opportunistic bacterial pathogen, Pseudomonas aeruginosa

MA Brockhurst, A Buckling… - Proceedings of the …, 2005 - royalsocietypublishing.org
Pseudomonas aeruginosa is an opportunistic human pathogen that colonizes the lungs of
cystic fibrosis (CF) patients. CF lungs often contain a diverse range of P. aeruginosa …

[HTML][HTML] Pseudomonas aeruginosa genomic structure and diversity

J Klockgether, N Cramer, L Wiehlmann… - Frontiers in …, 2011 - frontiersin.org
The Pseudomonas aeruginosa genome (G+ C content 65–67%, size 5.5–7 Mbp) is made up
of a single circular chromosome and a variable number of plasmids. Sequencing of …

Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa

JR Dettman, N Rodrigue, SD Aaron… - Proceedings of the …, 2013 - National Acad Sciences
Pseudomonas aeruginosa is an opportunistic pathogen of humans and is a major cause of
morbidity and mortality in patients with cystic fibrosis (CF). Prolonged infection of the …

Comparative Genomics of Isolates of a Pseudomonas aeruginosa Epidemic Strain Associated with Chronic Lung Infections of Cystic Fibrosis Patients

J Jeukens, B Boyle, I Kukavica-Ibrulj, MM Ouellet… - PloS one, 2014 - journals.plos.org
Pseudomonas aeruginosa is the main cause of fatal chronic lung infections among
individuals suffering from cystic fibrosis (CF). During the past 15 years, particularly …

Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment

R Hilker, A Munder, J Klockgether… - Environmental …, 2015 - Wiley Online Library
The population genomics of P seudomonas aeruginosa was analysed by genome
sequencing of representative strains of the 15 most frequent clonal complexes in the P …

Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species

J Mosquera-Rendón, AM Rada-Bravo… - BMC genomics, 2016 - Springer
Background Drug treatments and vaccine designs against the opportunistic human
pathogen Pseudomonas aeruginosa have multiple issues, all associated with the diverse …

In vivo functional genomics of Pseudomonas aeruginosa for high‐throughput screening of new virulence factors and antibacterial targets

E Potvin, DE Lehoux, I Kukavica‐Ibrulj… - Environmental …, 2003 - Wiley Online Library
Pseudomonas aeruginosa is a model for studying opportunistic pathogens that are highly
resistant to most classes of antibiotics and cause chronic pulmonary infections. We have …