Risk factors for anti‐drug antibody formation to infliximab: Secondary analyses of a randomised controlled trial
MK Brun, GL Goll, KK Jørgensen… - Journal of internal …, 2022 - Wiley Online Library
Abstract Background Anti‐drug antibodies (ADAb) frequently form early in the treatment
course of infliximab and other tumour necrosis factor (TNF) inhibitors, leading to treatment …
course of infliximab and other tumour necrosis factor (TNF) inhibitors, leading to treatment …
The frequency of anti-infliximab antibodies in patients with rheumatoid arthritis treated in routine care and the associations with adverse drug reactions and treatment …
SB Krintel, VP Grunert, ML Hetland, JS Johansen… - …, 2013 - academic.oup.com
Objectives. To investigate the frequency of anti-infliximab antibodies in patients with RA and
the associations with adverse drug reactions and treatment failure. Methods. Based on the …
the associations with adverse drug reactions and treatment failure. Methods. Based on the …
Influence of immunogenicity on the efficacy of long-term treatment with infliximab in rheumatoid arthritis
D Pascual-Salcedo, C Plasencia, S Ramiro… - …, 2011 - academic.oup.com
Objective. To analyse the clinical relevance of the production of anti-infliximab antibodies
(anti-infliximab Abs) in patients with RA undergoing infliximab treatment over a prolonged …
(anti-infliximab Abs) in patients with RA undergoing infliximab treatment over a prolonged …
[HTML][HTML] Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases
E Ducourau, D Mulleman, G Paintaud… - Arthritis research & …, 2011 - Springer
Introduction A proportion of patients receiving infliximab have antibodies toward infliximab
(ATI), which are associated with increased risk of infusion reaction and reduced response to …
(ATI), which are associated with increased risk of infusion reaction and reduced response to …
[HTML][HTML] Pharmacokinetic effects of antidrug antibodies occurring in healthy subjects after a single dose of intravenous infliximab
ED Ehrenpreis - Drugs in R&D, 2017 - Springer
Background Infliximab pharmacokinetic studies have been performed in patients receiving
chronic infliximab therapy. In these patients, infliximab antidrug antibodies (ADAs) increase …
chronic infliximab therapy. In these patients, infliximab antidrug antibodies (ADAs) increase …
Clinical consequences of infliximab immunogenicity and the effect of proactive therapeutic drug monitoring: exploratory analyses of the randomised, controlled NOR …
MK Brun, JE Gehin, KH Bjørlykke, DJ Warren… - The Lancet …, 2024 - thelancet.com
Background Antidrug antibodies to TNF inhibitors might affect clinical outcomes. Proactive
therapeutic drug monitoring allows for early detection of antidrug antibodies and might …
therapeutic drug monitoring allows for early detection of antidrug antibodies and might …
Detection of infliximab levels and anti‐infliximab antibodies: a comparison of three different assays
N Vande Casteele, DJ Buurman… - Alimentary …, 2012 - Wiley Online Library
Background Formation of antibodies to infliximab (ATI) inversely correlates with functional
drug levels and clinical outcome. Comparison of drug levels and anti‐drug antibody …
drug levels and clinical outcome. Comparison of drug levels and anti‐drug antibody …
[引用][C] Infliximab: additional safety data from an open label study.
CL Daniel, LW Moreland - The Journal of Rheumatology, 2002 - jrheum.org
Personal non-commercial use only. The Journal of Rheumatology Copyright© 2002. All
rights reserved. www. jrheum. org Downloaded on August 13, 2023 from serious adverse …
rights reserved. www. jrheum. org Downloaded on August 13, 2023 from serious adverse …
Assays for infliximab drug levels and antibodies: a matter of scales and categories
LI Bader, SM Solberg, SH Kaada… - Scandinavian …, 2017 - Wiley Online Library
Immunogenicity is a frequent cause of secondary non‐response to tumour necrosis factor
(TNF) inhibitors. Drug level measurement and detection of antidrug antibodies have been …
(TNF) inhibitors. Drug level measurement and detection of antidrug antibodies have been …
Anti-infliximab antibodies: How to compare old and new data?
M Imbrechts, T Van Stappen, G Compernolle… - … of Pharmaceutical and …, 2020 - Elsevier
Background Anti-drug-antibodies (ADA) against infliximab are frequently measured in
patients receiving infliximab treatment with loss of response and undetectable infliximab …
patients receiving infliximab treatment with loss of response and undetectable infliximab …