There has been a significant push in recent years to deploy fundamental knowledge and
methods of photochemistry toward biological ends. Photoreactive groups have enabled …

Light is arguably the most convenient non-invasive stimulant to perturb or control specific
chemical reactions in the biological systems. Upon light illumination, photosensitive …

The temporal and spatial regulation of protein function is central to biological processes.
Hence, the ability to artificially trigger molecular events in a biologically relevant context is …

Biological systems are characterized by a level of spatial and temporal organization that
often lies beyond the grasp of present day methods. Light-modulated bioreagents, including …

In biomedical sciences, the function of a protein of interest is investigated by altering its net
activity and assessing the consequences for the cell or organism. To change the activity of a …

Light is essential for various biochemical processes in all domains of life. In its presence
certain proteins inside a cell are excited, which either stimulates or inhibits subsequent …

Photolabile protecting groups enable biochemists to control the release of bioactive
compounds in living tissue.'Caged compounds'(photoactivatable bioagents) have become …

The photocontrol of protein functions, enzymatic reactions, and concomitantly biological
activities in living cells and organisms represents a rapidly developing and interdisciplinary …

Kinase-mediated phosphorylation of proteins and lipids plays a central role in the regulation
of intracellular signaling and cell functions in all eukaryotes.[1] Many kinases are maintained …

Light is unsurpassed in its ability to modulate biological interactions. Since their discovery,
chemists have been fascinated by photosensitive molecules capable of switching between …