[HTML][HTML] Targeting the Janus kinase family in autoimmune skin diseases
Autoimmune skin diseases are characterized by significant local and systemic inflammation
that is largely mediated by the Janus kinase (JAK)–signal transducer and activator of …
that is largely mediated by the Janus kinase (JAK)–signal transducer and activator of …
Janus kinase inhibitors in dermatology: Part I. A comprehensive review
The Janus kinase-signal transducer and activator of transcription (JAK-STAT) intracellular
signaling pathway is utilized by many proinflammatory molecules to mediate downstream …
signaling pathway is utilized by many proinflammatory molecules to mediate downstream …
Janus kinase inhibitors in dermatology: Part II. A comprehensive review
The Janus kinase-signal transducer and activator of transcription (JAK-STAT) intracellular
signaling pathway is implicated in the pathogenesis of a number of inflammatory …
signaling pathway is implicated in the pathogenesis of a number of inflammatory …
JAK inhibitors in dermatology: the promise of a new drug class
New molecularly targeted therapeutics are changing dermatologic therapy. Janus kinase–
signal transducer and activator of transcription (JAK-STAT) is an intracellular signaling …
signal transducer and activator of transcription (JAK-STAT) is an intracellular signaling …
Emerging therapies for atopic dermatitis: JAK inhibitors
DG Cotter, D Schairer, L Eichenfield - Journal of the American Academy of …, 2018 - Elsevier
The Janus kinase–signal transducer and activator of transcription pathway is a conserved
master regulator of immunity and myeloproliferation. Advanced understanding of this …
master regulator of immunity and myeloproliferation. Advanced understanding of this …
[HTML][HTML] Emerging topical and systemic JAK inhibitors in dermatology
F Solimani, K Meier, K Ghoreschi - Frontiers in immunology, 2019 - frontiersin.org
Accumulating data on cellular and molecular pathways help to develop novel therapeutic
strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic …
strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic …
Topical Janus kinase inhibitors: a review of applications in dermatology
AM Hosking, M Juhasz, NA Mesinkovska - Journal of the American …, 2018 - Elsevier
Background Janus kinase (JAK) inhibitors have attracted attention for their role in treating
inflammatory disorders. This new class of biologics has the potential to significantly affect the …
inflammatory disorders. This new class of biologics has the potential to significantly affect the …
Janus kinase (JAK) inhibitors for the treatment of skin and hair disorders: a review of literature
Janus kinase family (JAKs) has recently attracted the attention of many researchers, and
several JAK inhibitor drugs have been developed targeting different members of the JAK …
several JAK inhibitor drugs have been developed targeting different members of the JAK …
The emerging role of Janus kinase inhibitors in the treatment of autoimmune and inflammatory diseases
W Damsky, D Peterson, J Ramseier… - Journal of Allergy and …, 2021 - Elsevier
Autoimmune and inflammatory diseases are common and diverse, and they can affect
nearly any organ system. Much of the pathogenesis of these diseases is related to …
nearly any organ system. Much of the pathogenesis of these diseases is related to …
JAK-inhibitors in dermatology: current evidence and future applications
P Ciechanowicz, A Rakowska, M Sikora… - Journal of …, 2019 - Taylor & Francis
The Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway
is a ubiquitous intracellular signaling network. Selective JAK-inhibitors have anti …
is a ubiquitous intracellular signaling network. Selective JAK-inhibitors have anti …