Conserved cAMP signaling cascades regulate fungal development and virulence

CA D'Souza, J Heitman - FEMS microbiology reviews, 2001 - academic.oup.com
Two well characterized signal transduction cascades regulating fungal development and
virulence are the MAP kinase and cAMP signaling cascades. Here we review the current …

Signaling via cAMP in fungi: interconnections with mitogen-activated protein kinase pathways

J Kronstad, A De Maria, D Funnell, RD Laidlaw… - Archives of …, 1998 - Springer
The cAMP signal transduction pathway controls a wide variety of processes in fungi. For
example, considerable progress has been made in describing the involvement of cAMP …

OF SMUTS, BLASTS, MILDEWS, AND BLIGHTS: cAMP Signaling in Phytopathogenic Fungi

N Lee, CA D'Souza, JW Kronstad - Annual review of …, 2003 - annualreviews.org
▪ Abstract cAMP regulates morphogenesis and virulence in a wide variety of fungi including
the plant pathogens. In saprophytic yeasts such as Saccharomyces cerevisiae, cAMP …

cAMP signalling in pathogenic fungi: control of dimorphic switching and pathogenicity

MI Borges-Walmsley, AR Walmsley - Trends in microbiology, 2000 - cell.com
Morphological changes in pathogenic fungi often underlie the development of virulence and
infection by these organisms. Our knowledge of the components of the cell signalling …

Signal transduction cascades regulating fungal development and virulence

KB Lengeler, RC Davidson, C D'souza… - Microbiology and …, 2000 - Am Soc Microbiol
Cellular differentiation, mating, and filamentous growth are regulated in many fungi by
environmental and nutritional signals. For example, in response to nitrogen limitation …

MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea.

JR Xu, JE Hamer - Genes & development, 1996 - genesdev.cshlp.org
Many fungal pathogens invade plants using specialized infection structures called
appressoria that differentiate from the tips of fungal hyphae contacting the plant surface. We …

MAP Kinase and cAMP Signaling Pathways Modulate the pH-Induced Yeast-to-Mycelium Dimorphic Transition in the Corn Smut Fungus Ustilago maydis

AD Martínez-Espinoza, J Ruiz-Herrera… - Current …, 2004 - Springer
Acid pH induces the yeast-to-mycelium transition in haploid cells of Ustilago maydis. We
tested two signal transduction pathways known to be involved in dimorphism for roles in acid …

The cAMP/Protein Kinase A Pathway Regulates Virulence and Adaptation to Host Conditions in Cryptococcus neoformans

M Caza, JW Kronstad - Frontiers in cellular and infection microbiology, 2019 - frontiersin.org
Nutrient sensing is critical for adaptation of fungi to environmental and host conditions. The
conserved cAMP/PKA signaling pathway contributes to adaptation by sensing the …

Adenylyl Cyclase-Associated Protein Aca1 Regulates Virulence and Differentiation of Cryptococcus neoformans via the Cyclic AMP-Protein Kinase A Cascade

YS Bahn, JK Hicks, SS Giles, GM Cox, J Heitman - Eukaryotic cell, 2004 - Am Soc Microbiol
The evolutionarily conserved cyclic AMP (cAMP) signaling pathway controls cell functions in
response to environmental cues in organisms as diverse as yeast and mammals. In the …

Signal transduction cascades regulating pseudohyphal differentiation of Saccharomyces cerevisiae

X Pan, T Harashima, J Heitman - Current opinion in microbiology, 2000 - Elsevier
In response to nitrogen limitation, diploid cells of the yeast Saccharomyces cerevisiae
undergo a dimorphic transition to filamentous pseudohyphal growth. At least two signaling …