Monoamine-sensitive developmental periods impacting adult emotional and cognitive behaviors

D Suri, CM Teixeira, MKC Cagliostro… - …, 2015 - nature.com
Abstract Development passes through sensitive periods, during which plasticity allows for
genetic and environmental factors to exert indelible influence on the maturation of the …

New insights into how serotonin selective reuptake inhibitors shape the developing brain

JA Gingrich, H Malm, MS Ansorge, A Brown… - Birth defects …, 2017 - Wiley Online Library
Development passes through sensitive periods, during which plasticity allows for genetic
and environmental factors to exert indelible influence on the maturation of the organism. In …

Serotonin-related pathways and developmental plasticity: relevance for psychiatric disorders

A Dayer - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
Risk for adult psychiatric disorders is partially determined by early-life alterations occurring
during neural circuit formation and maturation. In this perspective, recent data show that the …

Serotonin-related rodent models of early-life exposure relevant for neurodevelopmental vulnerability to psychiatric disorders

TS Adjimann, CV Argañaraz, M Soiza-Reilly - Translational psychiatry, 2021 - nature.com
Mental disorders including depression and anxiety are continuously rising their prevalence
across the globe. Early-life experience of individuals emerges as a main risk factor …

Functional interplay between dopaminergic and serotonergic neuronal systems during development and adulthood

V Niederkofler, TE Asher… - ACS chemical …, 2015 - ACS Publications
The complex integration of neurotransmitter signals in the nervous system contributes to the
shaping of behavioral and emotional constitutions throughout development. Imbalance …

Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression

D Suri, G Zanni, D Mahadevia, N Chuhma, R Saha… - Molecular …, 2023 - nature.com
Sensitive developmental periods shape neural circuits and enable adaptation. However,
they also engender vulnerability to factors that can perturb developmental trajectories. An …

Neurocognitive development of motivated behavior: Dynamic changes across childhood and adolescence

DG Gee, KG Bath, CM Johnson, HC Meyer… - Journal of …, 2018 - Soc Neuroscience
The ability to anticipate and respond appropriately to the challenges and opportunities
present in our environments is critical for adaptive behavior. Recent methodological …

Serotonin signaling through prefrontal cortex 5-HT1A receptors during adolescence can determine baseline mood-related behaviors

AL Garcia-Garcia, Q Meng, S Canetta, AM Gardier… - Cell reports, 2017 - cell.com
Lifelong homeostatic setpoints for mood-related behaviors emerge during adolescence.
Serotonin (5-HT) plays an important role in refining the formation of brain circuits during …

From resilience to vulnerability: mechanistic insights into the effects of stress on transitions in critical period plasticity

BL Callaghan, BM Graham, S Li… - Frontiers in Psychiatry, 2013 - frontiersin.org
While early experiences are proposed to be important for the emergence of anxiety and
other mental health problems, there is little empirical research examining the impact of such …

Neurobehavioral evidence for changes in dopamine system activity during adolescence

D Wahlstrom, T White, M Luciana - Neuroscience & Biobehavioral Reviews, 2010 - Elsevier
Human adolescence has been characterized by increases in risk-taking, emotional lability,
and deficient patterns of behavioral regulation. These behaviors have often been attributed …