MCL1 Inhibition Overcomes the Aggressiveness Features of Triple-Negative Breast Cancer MDA-MB-231 Cells
G Pratelli, D Carlisi, D Di Liberto, A Notaro… - International Journal of …, 2023 - mdpi.com
Triple-Negative Breast Cancer (TNBC) is a particularly aggressive subtype among breast
cancers (BCs), characterized by anoikis resistance, high invasiveness, and metastatic …
cancers (BCs), characterized by anoikis resistance, high invasiveness, and metastatic …
Downregulation of MCL-1 and upregulation of PUMA using mTOR inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer
H Li, L Liu, H Chang, Z Zou, D Xing - Cell Death & Disease, 2018 - nature.com
Triple-negative breast cancer (TNBC) shows a higher malignant and poorer clinical outcome
compared with other breast cancer subtypes. Albeit that chemotherapy is the first choice for …
compared with other breast cancer subtypes. Albeit that chemotherapy is the first choice for …
Epithelial-mesenchymal transition and its regulators are major targets of triple-negative breast cancer
AE Al Moustafa - Cell adhesion & migration, 2013 - Taylor & Francis
Triple negative breast cancers (TNBCs) represent a distinct subtype of breast cancers that
are associated with early recurrence and an aggressive metastatic progression of the …
are associated with early recurrence and an aggressive metastatic progression of the …
Myeloid cell leukemia-1 is an important apoptotic survival factor in triple-negative breast cancer
CM Goodwin, OW Rossanese, ET Olejniczak… - Cell Death & …, 2015 - nature.com
Breast cancer is the second-most frequently diagnosed malignancy in US women. The triple-
negative breast cancer (TNBC) subtype, which lacks expression of the estrogen receptor …
negative breast cancer (TNBC) subtype, which lacks expression of the estrogen receptor …
MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer
Background Triple-negative breast cancer (TNBC) is a poor prognostic breast cancer with
the highest mutations and limited therapeutic choices. Cytokine networking between cancer …
the highest mutations and limited therapeutic choices. Cytokine networking between cancer …
COL8A1 enhances the invasion/metastasis in MDA-MB-231 cells via the induction of IL1B and MMP1 expression
A Sagara, S Miura, A Kobinata, R Naganawa… - Biochemical and …, 2023 - Elsevier
Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast
cancer with a high probability of metastasis and a lack of specific targets and targeted …
cancer with a high probability of metastasis and a lack of specific targets and targeted …
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function
KJ Campbell, SM Mason, ML Winder… - Cell Death & …, 2021 - nature.com
High levels of the anti-apoptotic BCL-2 family member MCL-1 are frequently found in breast
cancer and, appropriately, BH3-mimetic drugs that specifically target MCL-1's function in …
cancer and, appropriately, BH3-mimetic drugs that specifically target MCL-1's function in …
COL5A1 promotes triple-negative breast cancer progression by activating tumor cell-macrophage crosstalk
X Chen, C Ma, Y Li, Y Liang, T Chen, D Han, D Luo… - Oncogene, 2024 - nature.com
Triple-negative breast cancer (TNBC) is an exceptionally aggressive subtype of breast
cancer. Despite the recognized interplay between tumors and tumor-associated …
cancer. Despite the recognized interplay between tumors and tumor-associated …
Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
OA Bamodu, WC Huang, WH Lee, A Wu, LS Wang… - BMC cancer, 2016 - Springer
Background Triple negative breast cancers (TNBC) possess cell dedifferentiation
characteristics, carry out activities connate to those of cancer stem cells (CSCs) and are …
characteristics, carry out activities connate to those of cancer stem cells (CSCs) and are …
miR‐122‐5p promotes aggression and epithelial‐mesenchymal transition in triple‐negative breast cancer by suppressing charged multivesicular body protein 3 …
Z Wang, X Wang - Journal of cellular physiology, 2020 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is highly metastatic and frequently has a poor
prognosis. The lack of comprehension of TNBC and gene therapy targets has led to limitedly …
prognosis. The lack of comprehension of TNBC and gene therapy targets has led to limitedly …
相关搜索
- mcl1 inhibition aggressiveness features
- mda mb aggressiveness features
- mcl1 inhibition mda mb
- breast cancer aggressiveness features
- mcl1 inhibition breast cancer
- breast cancer mcl 1
- bh3 mimetics mcl 1
- breast cancer bh3 mimetics
- breast cancer mda mb
- breast cancer mesenchymal transition
- mda mb mmp1 expression
- breast cancer emt progression
- breast cancer survival factor
- breast cancer signaling axis
- breast cancer protein kinase
- upregulation of puma mcl 1