COVID-19 and inborn errors of immunity

OM Delmonte, R Castagnoli, LD Notarangelo - Physiology, 2022 - journals.physiology.org
Inborn errors of immunity (IEI) are a heterogeneous group of disorders affecting immune
host defense and immunoregulation. Considering the predisposition to develop severe and …

Impact of SARS-CoV-2 infection and COVID-19 on patients with inborn errors of immunity

SG Tangye, L Abel, S Al-Muhsen, A Aiuti… - Journal of Allergy and …, 2023 - Elsevier
Since the arrival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in
December 2019, its characterization as a novel human pathogen, and the resulting …

COVID-19 in the context of inborn errors of immunity: a case series of 31 patients from Mexico

LM Castano-Jaramillo… - Journal of clinical …, 2021 - Springer
Introduction Patients with inborn errors of immunity (IEI) have a compromised or
inappropriate immune response. Although they might be considered a high-risk group for …

Adverse COVID‐19 outcomes in immune deficiencies: Inequality exists between subclasses

E Karakoc Aydiner, S Bilgic Eltan, R Babayeva… - Allergy, 2022 - Wiley Online Library
Background Genetic deficiencies of immune system, referred to as inborn errors of immunity
(IEI), serve as a valuable model to study human immune responses. In a multicenter …

Inborn errors of immunity: Recent progress

N Seth, KS Tuano, J Chinen - Journal of Allergy and Clinical Immunology, 2021 - Elsevier
Recent advances in the field of inborn errors of immunity (IEIs) have been wide in scope,
including progress in mechanisms of disease, diagnosis, and management. New gene …

[HTML][HTML] Coronavirus disease 2019 in patients with inborn errors of immunity: an international study

I Meyts, G Bucciol, I Quinti, B Neven, A Fischer… - Journal of Allergy and …, 2021 - Elsevier
Background There is uncertainty about the impact of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI) …

Coronavirus disease 2019 in patients with inborn errors of immunity: lessons learned

G Bucciol, SG Tangye, I Meyts - Current opinion in pediatrics, 2021 - journals.lww.com
We review the characteristics of SARS-CoV-2 infection in a large number of patients with IEI.
Overall, we found that combined immunodeficiencies, immune dysregulation disorders, and …

Clinical management of patients with primary immunodeficiencies during the COVID-19 pandemic

I Quinti, I Mezzaroma, C Milito - Expert Review of Clinical …, 2021 - Taylor & Francis
ABSTRACT Introduction: Patients affected by Inborn Errors of Immunity (IEI) represent a
potential group-at-risk in the current COVID-19 pandemic. Studies on large and small …

Risk factors for severe COVID-19 and hospital admission in patients with inborn errors of immunity-results from a multicenter nationwide study

T Milota, M Sobotkova, J Smetanova… - Frontiers in …, 2022 - frontiersin.org
Despite the progress in the understanding how COVID-19 infection may impact
immunocompromised patients, the data on inborn errors of immunity (IEI) remain limited and …

COVID-19 in unvaccinated patients with inborn errors of immunity—polish experience

S Kołtan, M Ziętkiewicz, E Grześk, R Becht… - Frontiers in …, 2022 - frontiersin.org
At the beginning of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
pandemic, patients with inborn errors of immunity (IEI) appeared to be particularly …