Materials and Methods: Retrospective study of a prospectively maintained database of 3600
patients attending a single center was conducted. Patients with histologically confirmed …

Background Intravenous (IV) steroids remain the first-line treatment for patients with acute
ulcerative colitis (UC). However, 30% of patients do not respond to steroids, requiring …

Background The long‐term outcome of patients with acute severe ulcerative colitis (ASUC)
responding to intravenous steroids (IVS) has been poorly reported. Aims To assess relapse …

Background & Aims There is consensus on the criteria used to define acute severe
ulcerative colitis (ASUC) and on patient management, but it has been a challenge to identify …

Background & Aims. A severe flare-up develops in approximately 15% of patients with
ulcerative colitis (UC). It is questionable whether the response to the first parenteral …

Background There are limited data regarding clinical outcomes in ulcerative colitis (UC)
patients who require early corticosteroids (CS) use. Aim To evaluate the rate of early CS …

Objectives We aimed to determine whether changes in acute severe colitis (ASC)
management have translated to improved outcomes and to develop a simple model …

Background & Aims: Colectomy is a potentially life-saving procedure for patients with severe
attacks of UC who fail medical therapy. We aimed to systematically review studies that …

Background Acute severe ulcerative colitis is categorised using the Truelove & Witts criteria.
The Travis and the Ho scores are calculated following 72 h of steroid treatment to identify …

Although systemic steroids remain as the gold standard for the treatment of acute moderate
to severe active ulcerative colitis (UC), 15–57% of patients do not achieve clinical remission …