The human immunodeficiency virus (HIV) genome encodes a total of three structural
proteins, two envelope proteins, three enzymes, and six accessory proteins. Studies over the …

Human immunodeficiency virus type 1 is a complex retrovirus encoding 15 distinct proteins.
Substantial progress has been made toward understanding the function of each protein, and …

The homodimeric HIV-1 protease is the target of some of the most effective antiviral AIDS
therapy, as it facilitates viral maturation by cleaving ten asymmetric and nonhomologous …

The human immunodeficiency virus type I (HIV-1) capsid protein is initially synthesized as
the central domain of the Gag polyprotein, and is subsequently proteolytically processed into …

The immunodeficiency virus type 1 is a complex retrovirus. In addition to genes that specify
the proteins of the virus particle and the replicative enzymes common to all retroviruses, HIV …

The human immunodeficiency virus (HIV) is the causative agent of AIDS. HIV belongs to a
unique virus family, the Retroviridae, a group of small, enveloped, positive-strand RNA …

Publisher Summary This chapter deals with the structure and function of the leader transcript
of human immunodeficiency virus (HIV-1) and HIV-2. Most of the RNA signals encoded by …

The HIV-1 matrix protein forms an icosahedral shell associated with the inner membrane of
the mature virus. Genetic analyses have indicated that the protein performs important …

The classification of a new agent, ie its grouping to a defined virus family, is facilitated by
electron microscopical investigations. Depending on the method used, the different distinct …

X-ray diffraction analysis of a human immunodeficiency virus (HIV-1) capsid (CA) protein
shows that each monomer within the dimer consists of seven α-helices, five of which are …