Background Ocular infections caused by antibiotic-resistant pathogens can result in partial
or complete vision loss. The development of pan-resistant microbial strains poses a …

Peptoids are peptidomimetics that have attracted considerable interest as a promising class
of antimicrobials against multi-drug-resistant bacteria due to their resistance to proteolysis …

Purpose The purpose of this research work was to develop new polycationic compounds
based on pyridine and piperidine structures with high antimicrobial activities against …

Purpose: Pseudomonas aeruginosa is a leading cause of corneal infections. Recently, we
discovered an antimicrobial drug combination, polymyxin B/trimethoprim (PT)+ rifampin, that …

Bacterial pathogens are often involved in contact lens‐related adverse responses. This
study aimed to find antimicrobial peptides and proteins that effectively eradicate or inhibit …

Peptoids differ from peptides in that peptoids are composed of N-substituted rather than
alpha-carbon-substituted glycine units. In this paper we report the in vitro and in vivo …

Background: Antimicrobial peptides (AMPs) are short, cationic, amphipathic molecules that
have gained tremendous popularity as alternatives to traditional antibiotics due to their lower …

Bacterial keratitis causes significant blindness, yet antimicrobial resistance has rendered
current treatments ineffective. Polymyxin B-trimethoprim (PT) plus rifampin has potent in vitro …

Antibiotic resistance is increasing even in ocular pathogens, therefore the interest towards
antiseptics in Ophthalmology is growing. The aim of this study was to analyze the in vitro …

Purpose To investigate the ability of protamine, alone or in combination with other
antimicrobial agents, to kill bacteria and fungi associated with contact lens–related keratitis …