[HTML][HTML] Cryptococcus neoformans Is Resistant to Surfactant Protein A Mediated Host Defense Mechanisms

SS Giles, AK Zaas, MF Reidy, JR Perfect, JR Wright - PLoS One, 2007 - journals.plos.org
Initiation of a protective immune response to infection by the pathogenic fungus
Cryptococcus neoformans is mediated in part by host factors that promote interactions …

Surfactant Protein D Increases Phagocytosis of Hypocapsular Cryptococcus neoformans by Murine Macrophages and Enhances Fungal Survival

S Geunes-Boyer, TN Oliver, G Janbon… - Infection and …, 2009 - Am Soc Microbiol
Cryptococcus neoformans is a facultative intracellular opportunistic pathogen and the
leading cause of fungal meningitis in humans. In the absence of a protective cellular …

Enhanced Innate Immune Responsiveness to Pulmonary Cryptococcus neoformans Infection Is Associated with Resistance to Progressive Infection

L Guillot, SF Carroll, R Homer… - Infection and immunity, 2008 - Am Soc Microbiol
Genetically regulated mechanisms of host defense against Cryptococcus neoformans
infection are not well understood. In this study, pulmonary infection with the moderately …

Impact of surfactant protein D, interleukin-5, and eosinophilia on Cryptococcosis

SM Holmer, KS Evans, YG Asfaw, D Saini… - Infection and …, 2014 - Am Soc Microbiol
Cryptococcus neoformans is an opportunistic fungal pathogen that initiates infection
following inhalation. As a result, the pulmonary immune response provides a first line of …

Surfactant protein D facilitates Cryptococcus neoformans infection

S Geunes-Boyer, MF Beers, JR Perfect… - Infection and …, 2012 - Am Soc Microbiol
Concurrent with the global escalation of the AIDS pandemic, cryptococcal infections are
increasing and are of significant medical importance. Furthermore, Cryptococcus …

Pulmonary surfactant protein A binds to Cryptococcus neoformans without promoting phagocytosis

Walenkamp, Verheul, Scharringa… - European journal of …, 1999 - Wiley Online Library
Background Evidence is accumulating that the alveolar collectin surfactant protein A (SP‐A)
plays an important role in the first line of defence against infiltrating pathogenic micro …

Aggregation of Cryptococcus neoformans by Surfactant Protein D Is Inhibited by Its Capsular Component Glucuronoxylomannan

JK Van de Wetering, FEJ Coenjaerts… - Infection and …, 2004 - Am Soc Microbiol
Cryptococcus neoformans is an opportunistic pathogen invading the immunocompromised
host. Infection starts with the inhalation of acapsular or sparsely encapsulated cells, after …

Paradoxical roles of alveolar macrophages in the host response to Cryptococcus neoformans

TJ McQuiston, PR Williamson - Journal of Infection and Chemotherapy, 2012 - Elsevier
Cryptococcus neoformans (Cn) is a fungal pathogen that is a serious health threat to
immunocompromised individuals. Upon environmental exposure, infectious fungal …

[HTML][HTML] Pulmonary infection with an interferon-γ-producing Cryptococcus neoformans strain results in classical macrophage activation and protection

SE Hardison, S Ravi, KL Wozniak, ML Young… - The American journal of …, 2010 - Elsevier
Alternative macrophage activation is associated with exacerbated disease in murine models
of pulmonary cryptococcosis. The present study evaluated the efficacy of interferon-γ …

Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages

T McQuiston, C Luberto, M Del Poeta - Microbiology, 2011 - microbiologyresearch.org
The pathogenic fungus Cryptococcus neoformans is a major cause of morbidity and
mortality in immunocompromised individuals. Infection of the human host occurs through …