Dietary restriction (DR) delays or prevents age-related diseases and extends lifespan in
species ranging from yeast to primates. Although the applicability of this regimen to humans …

Resveratrol, a polyphenol found in several vegetal sources, has been shown to possess
lifespan-promoting properties in yeast and metazoans, including small mammals. While in …

Studies show that the plant polyphenol resveratrol can extend the life span of yeast, worms,
flies, and fish. It also mitigates the metabolic dysfunction of mice fed high-fat diets …

The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the
recent years, this compound received renewed interest as several findings implicated …

Age is the most important risk factor for diseases affecting the Western world, and slowing
age‐related degeneration would greatly improve the quality of human life. In rodents, caloric …

Dietary restriction (DR) increases lifespan in a range of evolutionarily distinct species. The
polyphenol resveratrol may be a dietary mimetic of some effects of DR. The pivotal role of …

Calorie restriction extends lifespan and confers metabolic benefits similar to the effect of
lifestyle interventions. Poor compliance to long-term dietary restriction, however, hinders the …

A small molecule that safely mimics the ability of dietary restriction (DR) to delay age-related
diseases in laboratory animals is greatly sought after. We and others have shown that …

In the search for novel preventive and therapeutic modalities in the management of
metabolic diseases and obesity, resveratrol has attracted great attention over the past …

The number of people suffering from metabolic disorders is dramatically increasing
worldwide. The need for new therapeutic strategies to combat this growing epidemic of …