Enhancing the apoptotic effect of IL-24/mda-7 on the human hepatic stellate cell through RGD peptide modification

I Jamhiri, S Zahri, D Mehrabani… - Immunological …, 2018 - Taylor & Francis
Induction of apoptosis or quiescent hepatic stellate cells (HSCs) can be an attractive
molecular strategy due to the importance of activation of HSCs during hepatic fibrogenesis …

[HTML][HTML] Effect of RGD coupled MDA-7/IL-24 on apoptosis induction in a hepatocellular carcinoma cell line

E Hosseini, SY Hosseini… - Molecular …, 2017 - spandidos-publications.com
The melanoma differentiation-associated gene‑7 (MDA-7) gene, also termed interleukin‑24
(IL‑24), is a tumor suppressor gene that induces apoptosis in a broad scope of malignant …

Adenovirus vector expressing MDA-7/IL-24 selectively induces growth arrests and apoptosis in human hepatocellular carcinoma cell lines independent of the state of …

XB Xue, JW Zheng, CJ Wang, K Chen… - Zhonghua gan Zang …, 2006 - europepmc.org
Objective To investigate the effect of melanoma differentiation associated gene-7/interleukin
24 (MDA/IL-24) on human hepatocellular carcinoma cell lines HepG2, MHCC97L and …

Melanoma differentiation associated gene-7 and interleukin-24 selectively induces growth arrest and apoptosis in hepatocellular carcinoma cell lines in vitro

CJ Wang, ZH Peng, Y Yu, K Chen… - Zhonghua wai ke za …, 2007 - europepmc.org
Objective To investigate the effect of melanoma differentiation associated gene-7/interleukin-
24 (mda-7/IL-24) on the hepatocellular carcinoma cell lines and normal liver cell line in vitro …

Effects of melanoma differentiation associated gene-7 (MDA-7/IL-24) on apoptosis of liver cancer cells via regulating the expression of B-cell lymphoma-2

Q Mo, L Liu, G Bao, T Li - Oncology Letters, 2019 - spandidos-publications.com
The present study investigated the mechanism of selective killing of liver cancer cells of
melanoma differentiation associated gene-7 (MDA-7, also called IL-24α) in order to provide …

The pattern of IL‑24/mda‑7 and its cognate receptors expression following activation of human hepatic stellate cells

I Jamhiri, SY Hosseini, D Mehrabani… - Biomedical …, 2017 - spandidos-publications.com
Activation of hepatic stellate cells (HSCs) is the pivotal event during liver fibrosis. Interleukin
(IL)‑24/melanoma differentiation‑associated gene‑7 (mda‑7) has attracted attention in the …

Oncolytic adenovirus-mediated MDA-7/IL-24 overexpression enhances antitumor activity in hepatocellular carcinoma cell lines.

CW Xiao, XB Xue, H Zhang, W Gao, Y Yu… - Hepatobiliary & …, 2010 - europepmc.org
Background Melanoma differentiation-associated gene-7 (MDA-7)/interleukin-24 (IL-24) is a
novel tumor suppressor gene, which has suppressor activity in a broad spectrum of human …

[HTML][HTML] MDA-7/IL-24 suppresses tumor adhesion and invasive potential in hepatocellular carcinoma cell lines

W Huo, ZM Li, XM Zhu, YM Bao… - Oncology …, 2013 - spandidos-publications.com
Melanoma differentiation associated gene-7 (MDA-7)/interleukin‑24 (IL-24) has been
considered as a tumor-suppressor gene, which suppresses the growth and induces the …

Enhanced Apoptosis-Inducing Function of MDA-7/IL-24 RGD Mutant Via the Increased Adhesion to Tumor Cells

DS Pei, ZX Yang, BF Zhang, XX Yin, LT Li… - Journal of Interferon & …, 2012 - liebertpub.com
Melanoma differentiation-associated gene-7 (mda-7)/interleukin-24 (IL-24) has shown
potent tumor cell apoptosis inducing capacity in multiple cancers. However, the apoptosis …

Construction and expression of recombinant adenovirus encoding MDA-7/IL-24 and its inhibitory effect on proliferation in human hepatocellular carcinoma cells

X Zhang, YL Meng, L Wang, J Zhao, B Yan… - Xi bao yu fen zi Mian …, 2011 - europepmc.org
Aim To construct recombinant plasmid and adenovirus harboring MDA-7 gene, and to
investigate its biological function on the proliferation of human hepatocellular carcinoma …