Golden exosomes selectively target brain pathologies in neurodegenerative and neurodevelopmental disorders
Exosomes, nanovesicles that are secreted by different cell types, enable intercellular
communication at local or distant sites. Alhough they have been found to cross the blood …
communication at local or distant sites. Alhough they have been found to cross the blood …
In Vivo Neuroimaging of Exosomes Using Gold Nanoparticles
Exosomes are emerging as effective therapeutic tools for various pathologies. These
extracellular vesicles can bypass biological barriers, including the blood-brain barrier, and …
extracellular vesicles can bypass biological barriers, including the blood-brain barrier, and …
Exosomes based strategies for brain drug delivery
Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …
[HTML][HTML] Engineered exosomes: desirable target-tracking characteristics for cerebrovascular and neurodegenerative disease therapies
As extracellular vesicles secreted by cells, exosomes are intercellular signalosomes for cell
communication and pharmacological effectors. Because of their special properties, including …
communication and pharmacological effectors. Because of their special properties, including …
[HTML][HTML] Overcoming the blood-brain barrier: Exosomes as theranostic nanocarriers for precision neuroimaging
C Li, S Qin, Y Wen, W Zhao, Y Huang, J Liu - Journal of Controlled Release, 2022 - Elsevier
Exosomes are cell-derived vesicles with a lipid bilayer membrane that play important roles
in intercellular communication. They provide an unprecedented opportunity for the …
in intercellular communication. They provide an unprecedented opportunity for the …
[HTML][HTML] Exosomes: origins and therapeutic potential for neurodegenerative disease
DK Sarko, CE McKinney - Frontiers in neuroscience, 2017 - frontiersin.org
Exosomes, small lipid bilayer vesicles, are part of the transportable cell secretome that can
be taken up by nearby recipient cells or can travel through the bloodstream to cells in distant …
be taken up by nearby recipient cells or can travel through the bloodstream to cells in distant …
[HTML][HTML] Brain derived exosomes are a double-edged sword in Alzheimer's disease
Z Song, Y Xu, W Deng, L Zhang, H Zhu, P Yu… - Frontiers in Molecular …, 2020 - frontiersin.org
Brain derived exosomes (BDEs) are extracellular nanovesicles that are collectively released
by all cell lineages of the central nervous system and contain cargo from their original cells …
by all cell lineages of the central nervous system and contain cargo from their original cells …
[HTML][HTML] Diagnostic and therapeutic potential of exosomes in neurodegenerative diseases
P Gao, X Li, X Du, S Liu, Y Xu - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Neurodegenerative diseases are closely related to brain function and the progression of the
diseases are irreversible. Due to brain tissue being not easy to acquire, the study of the …
diseases are irreversible. Due to brain tissue being not easy to acquire, the study of the …
The application of exosomes and exosome-nanoparticle in treating brain disorders
Brain-derived exosomes (BDEs) are extracellular nanovesicles released by all central
nervous system cell lineages and contain cargo from the cells that produced them. In …
nervous system cell lineages and contain cargo from the cells that produced them. In …
Diagnostic and therapeutic potentials of exosomes in CNS diseases
I Kawikova, PW Askenase - Brain research, 2015 - Elsevier
A newly discovered cell-to-cell communication system involves small, membrane-enveloped
nanovesicles, called exosomes. We describe here how these extracellular nanoparticles …
nanovesicles, called exosomes. We describe here how these extracellular nanoparticles …