Diabetic neuropathy (DN) is a common complication of diabetes mellitus that is hardly
reversible at the late stages. Since treatment of neuropathic pain is predominantly …

The present study was designed to investigate the anti-allodynic effects of current analgesic
agents, such as pregabalin, amitriptyline, mexiletine, morphine, and diclofenac, in a rat …

Painful diabetic neuropathy is one of the most common forms of neuropathic pain
syndromes. Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine that has …

Painful neuropathy, a common complication of diabetes mellitus is characterized by
allodynia and hyperalgesia. Recent studies emphasized on the role of non-neuronal cells …

Background In experimental early painful diabetic neuropathy, persistent hyperglycaemia
induces dys‐regulated sodium channel (N avs) expression in the dorsal root ganglion …

Background This study investigated the role of NR2B in a modulated pain process in the
painful diabetic neuropathy (PDN) rat using various pain stimuli. Methods Thirty-two …

Diabetic neuropathic pain is a common complication of diabetes mellitus and requires a
substantial amount of societal resources. Pyridoxamine is an inhibitor of advanced glycation …

BACKGROUND: Lidocaine is used clinically for tactile allodynia associated with diabetes-
induced neuropathy. Although the analgesic effect of lidocaine through suppression of …

Objectives: Neuropathic pain reduces the life qualities of patients with Diabetes mellitus.
Clinical guidelines recommend relief in diabetic neuropathic pain through the use of some …

Painful neuropathy is one of the most common complications of diabetes, one hallmark of
which is tactile allodynia (pain hypersensitivity to innocuous stimulation). The underlying …