[HTML][HTML] Emodin attenuates bleomycin-induced pulmonary fibrosis via anti-inflammatory and anti-oxidative activities in rats

SL Tian, Y Yang, XL Liu, QB Xu - Medical Science Monitor …, 2018 - ncbi.nlm.nih.gov
Background Idiopathic pulmonary fibrosis (IPF) can severely damage lung function, which
may result in death. Emodin is a major ingredient of rhubarb and has been proven to protect …

Emodin alleviates bleomycin-induced pulmonary fibrosis in rats

R Guan, X Zhao, X Wang, N Song, Y Guo, X Yan… - Toxicology Letters, 2016 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with few treatment options and
poor prognosis. Emodin, extracted from Chinese rhubarb, was found to be able to alleviate …

[HTML][HTML] Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation

R Guan, X Wang, X Zhao, N Song, J Zhu, J Wang… - Scientific reports, 2016 - nature.com
Aberrant activation of TGF-β1 is frequently encountered and promotes epithelial-
mesenchymal transition (EMT) and fibroblast activation in pulmonary fibrosis. The present …

[HTML][HTML] Eucalyptol prevents bleomycin-induced pulmonary fibrosis and M2 macrophage polarization

Y Rui, X Han, A Jiang, J Hu, M Li, B Liu, F Qian… - European Journal of …, 2022 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial pneumonia
with limited therapeutic options. Eucalyptol, a terpenoid oxide isolated from eucalyptus …

GSPE Protects against Bleomycin‐Induced Pulmonary Fibrosis in Mice via Ameliorating Epithelial Apoptosis through Inhibition of Oxidative Stress

OJ Sul, JH Kim, T Lee, KW Seo, HJ Cha… - Oxidative Medicine …, 2022 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease of
unknown cause which leads to alveolar epithelial cell apoptosis followed by basement …

[HTML][HTML] Protective effects of Rosavin on bleomycin-induced pulmonary fibrosis via suppressing fibrotic and inflammatory signaling pathways in mice

X Xin, D Yao, K Zhang, S Han, D Liu, H Wang… - Biomedicine & …, 2019 - Elsevier
Idiopathic Pulmonary fibrosis (IPF) is diagnosed as a life-threatening, progressive and
incurable lung disease characterized by accumulation of extracellular matrix and …

[HTML][HTML] Hesperidin ameliorates bleomycin-induced experimental pulmonary fibrosis via inhibition of TGF-beta1/Smad3/AMPK and IkappaBalpha/NF-kappaB …

Z Zhou, AD Kandhare, AA Kandhare… - EXCLI …, 2019 - ncbi.nlm.nih.gov
Bleomycin (BLM) is a chemotherapeutic agent which is associated with Idiopathic
pulmonary fibrosis (IPF) due to its chronic administration. Hesperidin, a bioflavonoid has …

Inhibitory effect of emodin on bleomycin‐induced pulmonary fibrosis in mice

XH Chen, RS Sun, JM Hu, ZY Mo… - Clinical and …, 2009 - Wiley Online Library
SUMMARY 1 Currently, there is no satisfactory treatment for pulmonary fibrosis. Emodin, a
component in Chinese herbs, has been shown to have an antifibrotic effect on pancreatic …

Zingerone ameliorates oxidative stress and inflammation in bleomycin-induced pulmonary fibrosis: modulation of the expression of TGF-β1 and iNOS

H Gungor, M Ekici, M Onder Karayigit… - Naunyn-Schmiedeberg's …, 2020 - Springer
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease with limited treatment
options. Zingerone found in ginger (Zingiber officinale L.) has many pharmacological effects …

[HTML][HTML] Wedelolactone attenuates pulmonary fibrosis partly through activating AMPK and regulating Raf-MAPKs signaling pathway

J Yang, L Tao, B Liu, X You, C Zhang, H Xie… - Frontiers in …, 2019 - frontiersin.org
Pulmonary fibrosis is common in a variety of inflammatory lung diseases, there is currently
no effective clinical drug treatment. It has been reported that the ethanol extract of Eclipta …