The concept of lysosomotropic agents significantly changed numerous aspects of cellular
biochemistry, biochemical pharmacology, and clinical medicine. In the present review, we …

Introduction: Autophagy is a lysosome-dependent degradation pathway that maintains
cellular homeostasis in response to a variety of cellular stresses. Accumulating reports …

Introduction Small molecules targeting autophagy have been highly implicated as new
therapeutic agents to treat diseases of interest. With the increasing demand for autophagy …

Autophagy is pivotal in the maintenance of organelle function and intracellular nutrient
balance. Besides the role of autophagy in the homeostasis and physiology of the individual …

Autophagy, a process of self-digestion of the cytoplasm and organelles through which
cellular components are recycled for reuse or energy production, is an evolutionarily …

Background: Naturally-occurring products derived from living organisms have been shown
to modulate various pharmacological and biological activities. Natural products protect …

Introduction: Autophagy is an intracellular process of self-digestion involving the lysosomal
degradation of cytoplasmic organelles and macromolecules. It occurs at low basal levels to …

Natural compounds derived from living organisms are well defined for their remarkable
biological and pharmacological properties likely to be translated into clinical use. Therefore …

Autophagy is central to the maintenance of organismal homeostasis in both physiological
and pathological situations. Accordingly, alterations in autophagy have been linked to …

Autophagy is an important intracellular catabolic mechanism critically involved in regulating
tissue homeostasis. The implication of autophagy in human diseases and the need to …