For successful future therapeutic strategies for tinnitus and hyperacusis, a subcategorization
of both conditions on the basis of differentiated neural correlates would be of invaluable …

Tinnitus is proposed to be caused by decreased central input from the cochlea, followed by
increased spontaneous and evoked subcortical activity that is interpreted as compensation …

Prolonged low-level noise exposure alters loudness perception in humans, presumably by
decreasing the gain of the central auditory system. Here we test the central gain hypothesis …

The etiology of tinnitus is known to be diverse in the human population. An appropriate
animal model of tinnitus should incorporate this pathological diversity. Previous studies …

Tinnitus is a phantom sound percept that is strongly associated with peripheral hearing loss.
However, only a fraction of hearing-impaired subjects develops tinnitus. This may be based …

Manipulations that enhance neuroplasticity may inadvertently create opportunities for
maladaptation. We have previously used passive exposures to non-traumatic white noise to …

Flavoprotein autofluorescence imaging was used to examine auditory cortical synaptic
responses in aged animals with behavioral evidence of tinnitus and hearing loss. Mice were …

Hyperacusis, a marked intolerance to normal environmental sound, is a common symptom
in patients with tinnitus, Williams syndrome, autism, and other neurologic diseases. It has …

Animal models of tinnitus allow us to study the relationship between changes in neural
activity and the tinnitus percept. Here, guinea pigs were subjected to unilateral noise trauma …

Background: Tinnitus and its mechanisms are an ongoing subject of interrogation in the
neuroscientific community. Although most current models agree that it encompasses …