Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice

Y Zhang, S Qin, Y Song, J Yuan, S Hu… - Frontiers in …, 2022 - frontiersin.org
Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown
algae, which is associated with beneficial health effects. Here, we aimed to investigate the …

Single-cell RNA sequencing analysis reveals alginate oligosaccharides preventing chemotherapy-induced mucositis

Y Zhao, Y Feng, M Liu, L Chen, Q Meng, X Tang… - Mucosal …, 2020 - nature.com
Worldwide the incidence of cancer has been continuing increasing. Mucositis of the
gastrointestinal tract is a common side effect in patients under chemotherapy. Anticancer …

Alginate Oligosaccharide Ameliorates D‐Galactose‐Induced Kidney Aging in Mice through Activation of the Nrf2 Signaling Pathway

H Pan, W Feng, M Chen, H Luan, Y Hu… - BioMed research …, 2021 - Wiley Online Library
Aging is an independent risk factor for the development of age‐related progressive kidney
injury. As a part of the aging process, kidney aging has been indicated to be associated with …

An exploration of alginate oligosaccharides modulating intestinal inflammatory networks via gut microbiota

Z Zhang, X Wang, F Li - Frontiers in Microbiology, 2023 - frontiersin.org
Alginate oligosaccharides (AOS) can be obtained by acidolysis and enzymatic hydrolysis.
The products obtained by different methods have different structures and physiological …

Lactobacillus rhamnosus Encapsulated in Alginate/Chitosan Microgels Manipulates the Gut Microbiome to Ameliorate Salt-Induced Hepatorenal Injury

Z Zhang, J Liu, M Li, B Yang, W Liu, Z Chu, B Cui… - Frontiers in …, 2022 - frontiersin.org
As the essential regulator of intestinal bacterial diversity, probiotics are a potential treatment
for chronic high-salt diet (HSD)–induced metabolic dysfunction. Probiotic cells entrapped in …

Alginate oligosaccharide ameliorates azithromycin-induced gut microbiota disorder via Bacteroides acidifaciens-FAHFAs and Bacteroides-TCA cycle axes

S Yan, Y Zhu, L Li, S Qin, J Yuan, X Chang, S Hu - Food & Function, 2023 - pubs.rsc.org
Alginate oligosaccharide is a kind of prebiotic with broad application prospects. However,
little attention is paid to the recovery effect of alginate oligosaccharide on disordered …

Gut microbiota mediates the protective effects of traditional chinese medicine formula Qiong-Yu-Gao against cisplatin-induced acute kidney injury

YT Zou, J Zhou, JH Zhu, CY Wu, H Shen… - Microbiology …, 2022 - Am Soc Microbiol
Our previous study found that Qiong-Yu-Gao (QYG), a traditional Chinese medicine formula
derived from Rehmanniae Radix, Poria, and Ginseng Radix, has protective effects against …

Alginate alleviates dextran sulfate sodium-induced colitis by promoting Bifidobacterium animalis and intestinal hyodeoxycholic acid synthesis in mice

Y Pi, X Zhang, Y Wu, Z Wang, Y Bai, X Liu… - Microbiology …, 2022 - Am Soc Microbiol
Alginate (ALG) is known to alleviate intestinal inflammation in inflammatory bowel disease,
but its mechanism of action remains elusive. In the present study, we studied the …

Alginate oligosaccharides prevent dextran-sulfate-sodium-induced ulcerative colitis via enhancing intestinal barrier function and modulating gut microbiota

A Wu, Y Gao, R Kan, P Ren, C Xue, B Kong, Q Tang - Foods, 2023 - mdpi.com
Alginate oligosaccharides are degradation products of alginate and have attracted
increasing attention due to their versatile biological functions. In the present study, C57BL/6 …

Algal oil alleviates antibiotic-induced intestinal inflammation by regulating gut microbiota and repairing intestinal barrier

H Zhang, Z Xu, W Chen, F Huang, S Chen… - Frontiers in …, 2023 - frontiersin.org
Introduction Taking antibiotics would interfere with gut microbiota and increase the risk of
opportunistic pathogen infection and inflammation. Methods In this study, 36 male C57BL/6 …