A multiple-trait Bayesian Lasso for genome-enabled analysis and prediction of complex traits

D Gianola, RL Fernando - Genetics, 2020 - academic.oup.com
A multiple-trait Bayesian LASSO (MBL) for genome-based analysis and prediction of
quantitative traits is presented and applied to two real data sets. The data-generating model …

Genome-enabled prediction using the BLR (Bayesian Linear Regression) R-package

G de Los Campos, P Perez, AI Vazquez… - Genome-wide association …, 2013 - Springer
The BLR (Bayesian linear regression) package of R implements several Bayesian
regression models for continuous traits. The package was originally developed for …

The Bayesian lasso for genome-wide association studies

J Li, K Das, G Fu, R Li, R Wu - Bioinformatics, 2011 - academic.oup.com
Motivation: Despite their success in identifying genes that affect complex disease or traits,
current genome-wide association studies (GWASs) based on a single SNP analysis are too …

Extended Bayesian LASSO for multiple quantitative trait loci mapping and unobserved phenotype prediction

CM Mutshinda, MJ Sillanpaa - Genetics, 2010 - academic.oup.com
Abstract The Bayesian LASSO (BL) has been pointed out to be an effective approach to
sparse model representation and successfully applied to quantitative trait loci (QTL) …

[HTML][HTML] Bayesian LASSO, scale space and decision making in association genetics

L Pasanen, L Holmström, MJ Sillanpää - PloS one, 2015 - journals.plos.org
Background LASSO is a penalized regression method that facilitates model fitting in
situations where there are as many, or even more explanatory variables than observations …

Multiple quantitative trait analysis using Bayesian networks

M Scutari, P Howell, DJ Balding, I Mackay - Genetics, 2014 - academic.oup.com
Abstract Models for genome-wide prediction and association studies usually target a single
phenotypic trait. However, in animal and plant genetics it is common to record information on …

[HTML][HTML] Bayesian group lasso for nonparametric varying-coefficient models with application to functional genome-wide association studies

J Li, Z Wang, R Li, R Wu - The annals of applied statistics, 2015 - ncbi.nlm.nih.gov
Although genome-wide association studies (GWAS) have proven powerful for
comprehending the genetic architecture of complex traits, they are challenged by a high …

[HTML][HTML] Enhancing genome-enabled prediction by bagging genomic BLUP

D Gianola, KA Weigel, N Krämer, A Stella, CC Schön - PLoS One, 2014 - journals.plos.org
We examined whether or not the predictive ability of genomic best linear unbiased
prediction (GBLUP) could be improved via a resampling method used in machine learning …

[HTML][HTML] Improved genetic prediction of complex traits from individual-level data or summary statistics

Q Zhang, F Privé, B Vilhjálmsson, D Speed - Nature communications, 2021 - nature.com
Most existing tools for constructing genetic prediction models begin with the assumption that
all genetic variants contribute equally towards the phenotype. However, this represents a …

[HTML][HTML] Genome-wide prediction using Bayesian additive regression trees

P Waldmann - Genetics Selection Evolution, 2016 - Springer
Background The goal of genome-wide prediction (GWP) is to predict phenotypes based on
marker genotypes, often obtained through single nucleotide polymorphism (SNP) chips. The …