Covering: up to 2023 Infusions of the plants Artemisia annua and A. afra are gaining broad
popularity to prevent or treat malaria. There is an urgent need to address this controversial …

Artemisinin-based combination therapies (ACT) are the frontline treatments against malaria
worldwide. Recently the use of traditional infusions from Artemisia annua (from which …

Application of traditional Chinese drug, artemisinin, originally derived from Artemisia annua
L., in malaria therapy has now been globally accepted. Artemisinin and its derivatives, with …

Covering: up to 2017–2022 Many small molecule drugs are first discovered in nature,
commonly the result of long ethnopharmacological use by people, and then characterized …

The 2015 Nobel Prize in Physiology or Medicine was awarded to Tu Youyou for her
“discoveries concerning a novel therapy against malaria”. Educated in pharmaceutical …

The malaria parasite Plasmodium falciparum is one of the world's most lethal pests,
accounting for over a million deaths per year. 90% of cases are in Sub-Saharan Africa, 85 …

Artemisinin, a sesquiterpene lactone produced by Artemisia annua glandular secretory
trichomes, is the active ingredient in the most effective treatment for uncomplicated malaria …

Artemisinins, as a class of bioactive molecules, are mainly derived from the extracts of
Artemisia annua L. and are the mainstay for malaria treatment, including severe malaria …

Drugs are primary weapons for reducing malaria in human populations. However
emergence of resistant parasites has repeatedly curtailed the lifespan of each drug that is …

Fifty years ago, in 1972, artemisinin was first isolated as a pure compound from Artemisia
annua L.(Asteraceae) and was shown to possess potent antimalarial properties. This review …